Secondary Intracranial Hypertension After Ciprofloxacin Treatment: A Case Report

Pena Acevedo L, Rodriguez Pena S
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Abstract

A 30-year-old man developed secondary osteomyelitis after a traumatic amputation of his right index finger. The infection was treated with ciprofloxacin. Approximately 4 weeks after starting treatment, he complained of a progressive decrease in visual acuity, retro-ocular pain and bitemporal headache. A diagnosis of intracranial hypertension was established. Blood sample analysis, infectious profile, cerebrospinal fluid analysis, and neuroimaging were normal. Visual acuity and other symptoms progressively improved after stopping drug treatment. There were no complications or sequelae. Intracranial hypertension due to fluoroquinolones is described in the medical literature, its appearance during such treatments, despite being a rare adverse event, should be monitored.
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环丙沙星治疗后继发颅内高压1例
一名30岁男子在右食指外伤性截肢后患上继发性骨髓炎。用环丙沙星治疗感染。开始治疗约4周后,患者主诉视力逐渐下降,眼后疼痛和双颞头痛。诊断为颅内高压。血样分析、感染谱、脑脊液分析和神经影像学检查均正常。停止药物治疗后,视力及其他症状逐渐改善。无并发症和后遗症。氟喹诺酮类药物引起的颅内高压在医学文献中有所描述,但其在此类治疗期间的出现,尽管是一种罕见的不良事件,但应加以监测。
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