Design and fabrication of hollow fiber-based Raman tweezers for bioparticle measurement

Y. Morisaki, T. Katagiri, Y. Matsuura
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Abstract

The flexible fiber optic probe for laser trapping Raman spectroscopy is developed to analyze single bio-particles in vivo. The probe consists of the hollow optical fiber and TiO2 micro-lens. Red blood cell and yeast are stably trapped by the fabricated probe. The Raman measurement of PMMA particle having 10 μm diameters is also demonstrated.
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用于生物颗粒测量的中空纤维拉曼镊子的设计与制造
开发了一种用于激光捕获拉曼光谱的柔性光纤探针,用于体内单个生物颗粒的分析。探头由中空光纤和TiO2微透镜组成。制备的探针可以稳定地捕获红细胞和酵母。对直径为10 μm的PMMA粒子进行了拉曼测量。
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