Pyrrolizidine alkaloids in Senecio vulgaris L. growing in Iceland.

Acta pharmaceutica Nordica Pub Date : 1990-01-01
K Ingolfsdóttir, P J Hylands
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Abstract

The distribution of toxic pyrrolizidine alkaloids in the Icelandic flora has been studied for the first time. In addition to the isolation of senecionine, seneciphylline, and retrorsine from Senecio vulgaris L., the presence of riddelline was confirmed by high resolution NMR spectroscopy. The presence of this alkaloid in S. vulgaris has previously been controversial. Furthermore, senecionine oxide and seneciphylline oxide were isolated by preparative centrifugal chromatography.

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产自冰岛的绿皮草中吡咯利西啶类生物碱。
对冰岛植物群中有毒吡咯利西啶类生物碱的分布进行了首次研究。通过高分辨率核磁共振谱分析,除分离出荆芥碱、荆芥碱和反逆转录酶外,还鉴定出荆芥碱的存在。这种生物碱在寻常草中的存在此前一直存在争议。采用制备离心色谱法分离得到了氧化油油果碱和氧化油油果碱。
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