Clinical Correlates Involving Deficiency of Vitamin D and Calcium

S. Galea, R. Blundell
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Abstract

: The effects of vitamin D and calcilllll deficiency are evident in several patients suffering from various diseases including osteoporosis and rickets. Other hormones such as glucocorticoids also playa role in bone homeostasis leading to bone growth promotion or retardation. Consequently, hormone imbalances in patients should be considered with suspected vitamin D and calcilllll deficiency. The deficiency of vitamin D and calciwn lead to non-bone related abnormalities for instance promotion of prostate cancer and retardation of blood clotting, respectively. However, this study will be focusing on the detrimental effects of osteoporosis and rickets on patients. Vitamin D and calcilllll deficiency may be prevented by adequate Sllll exposure as well as diet supplementation. Vitamin D and calcilllll deficiency result in lack of intracellular mechanisms, loss of bone matrix and density hence, weaker bones. This leads to an increased probability of bone fractures.
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缺乏维生素D和钙的临床相关性
维生素D和钙细胞缺乏症对骨质疏松症和佝偻病等多种疾病的影响非常明显。其他激素如糖皮质激素也在骨稳态中起作用,导致骨生长促进或迟缓。因此,激素失衡的患者应考虑与可疑的维生素D和钙细胞缺乏症。维生素D和钙的缺乏会导致与骨骼无关的异常,例如前列腺癌的增加和血液凝固的减慢。然而,这项研究将侧重于骨质疏松症和佝偻病对患者的有害影响。维生素D和钙钙缺乏症可以通过适当的接触和饮食补充来预防。维生素D和钙微球缺乏导致细胞内机制缺乏,骨基质和密度的损失,因此,骨骼较弱。这导致骨折的可能性增加。
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