Experimental testicular torsion--early and late morphological and enzymohistochemical changes.

L Ralitchkova, Z Nanov, D Gotchev, A Hinev, T Libald, R Wolnik
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Abstract

It has been reported that testicular torsion leads to diminished fertility. This experimental study includes 32 mature male Wistar rats, divided into 3 groups. Group 1 (4 animals) served as a control group. Group 2 (16 animals) underwent an unilateral definitive ligature of the testicular vessels. Group 3 (12 animals) underwent right testicular torsion at 360 degrees, followed by detorsion at 4, 12 or 24 hours. Both testicles were removed at different terms after the operation and processed for histologic and enzymohistochemical studies. The results of the experiment indicate that a certain recovery of the structure and the enzyme activity may be expected only in case if the duration of the torsion lasts not more than 4 hours. After this period severe and irreversible changes in the ipsilateral testis and serious alterations in the contralateral testis occur.

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实验性睾丸扭转-早期和晚期形态和酶组织化学变化。
据报道,睾丸扭转会导致生育能力下降。本实验选用32只成年雄性Wistar大鼠,分为3组。第一组(4只)为对照组。第二组(16只)接受单侧睾丸血管结扎术。第三组(12只)右睾丸360度扭转,分别在4、12、24小时扭转。在手术后不同时期切除两个睾丸,并进行组织学和酶组织化学研究。实验结果表明,只有在扭转持续时间不超过4小时的情况下,才能预期结构和酶活性的一定恢复。在此之后,同侧睾丸和对侧睾丸发生严重的不可逆变化。
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[New organ-preserving technics for third-grade splenic trauma. An experimental study]. [Cisplatin-induced nephrotoxic side effects of cytostatic chemotherapy of testicular tumors]. [The improvement of the tolerance of the kidney for ischemia with the prostacyclin analog iloprost]. [Diagnosis of rejection after pancreatic transplantation in the minipig model]. The effect of "end to side" portacaval anastomosis on regeneration ability of white rat liver.
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