Conceptual design of biosensors

Abstract

Design of biosensors refers to the field of interdisciplinary research, therefore, it is necessary to develop a unified systems approach that is invariant to the physical nature of the used phenomena and processes to create an automated system for conceptual design of such elements. It is appropriate to choose the fundamentals of non-equilibrium thermodynamics as the basis for the development of this approach. They allow to obtain a complete system of transfer equations of the phenomena of different physical nature and other laws, without opening their molecular mechanism. This article discusses the energy-information model of diffusion phenomena, as the processes of diffusion is the general type of the processes that is occurring in bioselective elements. A number of physical effects are described by this model. They are used in the conceptual design of electrochemical biosensors.