{"title":"Toxic effects of acute exposure to particular xylene isomers in animals.","authors":"Z Korsak, J A Sokal, T Wasiela, R Swiercz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of exposure to particular xylene isomers at a concentration of 3000 ppm on rotarod performance in rats and the respiratory rate in mice was investigated. Rotarod performance was tested in rats immediately after termination of a 6-hour exposure, and the respiratory rate in mice was recorded during a short 6 minute exposure to individual xylene isomers. In both rats and mice the toxic effects of exposure to ortho- and meta-xylene were more pronounced than that of para-xylene.</p>","PeriodicalId":77768,"journal":{"name":"Polish journal of occupational medicine","volume":"3 2","pages":"221-6"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of occupational medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The effect of exposure to particular xylene isomers at a concentration of 3000 ppm on rotarod performance in rats and the respiratory rate in mice was investigated. Rotarod performance was tested in rats immediately after termination of a 6-hour exposure, and the respiratory rate in mice was recorded during a short 6 minute exposure to individual xylene isomers. In both rats and mice the toxic effects of exposure to ortho- and meta-xylene were more pronounced than that of para-xylene.
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