[Relative frequency of glucose-6-phosphate dehydrogenase deficiency in jaundiced newborn infants in the metropolitan area of Monterrey, Nuevo León].

Archivos de investigacion medica Pub Date : 1990-07-01
G González-Quiroga, J L Ramírez del Río, R Ortíz-Jalomo, R F García-Contreras, R M Cerda-Flores, B D Mata-Cárdenas, R Garza-Chapa
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Abstract

In order to estimate the frequency of G6PD deficiency in the icteric population of the Monterrey metropolitan área (MMA), in the state of Nuevo León, there were studied 829 newborn males were studied. It was found that 13 subjects were deficient of this enzyme, that is equivalent to a frequency of 1.57% and when this frequency was compared with the one that was found an a previous study in a random sample of newborn males (0.66%) no statistical difference was observed, but it was estimated that the icteric newborn males have a relative risk of 2.34 times higher than the population in general to be a G6PD deficient, and this fact suggests the necessity to establish this screening test as a routine for all icteric newborn males, in order to have an opportune detection and an appropriate counselling.

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[蒙特雷市区黄疸新生儿葡萄糖-6-磷酸脱氢酶缺乏症的相对频率,Nuevo León]。
为了估计蒙特雷大都会área (MMA)黄疸人群中G6PD缺乏症的频率,在Nuevo León州对829名新生男性进行了研究。结果发现有13例受试者G6PD缺失,频率为1.57%,与以往随机抽样新生儿男性中发现的频率(0.66%)比较无统计学差异,但估计黄疸新生儿男性G6PD缺失的相对危险度为一般人群的2.34倍。这一事实表明,有必要将这种筛查试验作为所有黄疸新生儿的常规检查,以便及时发现和适当咨询。
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