Study of epileptic rat's EEG using bispectrum analysis

Wu Hongyi, Xia Yang, Lai Yongxiu, L. Yansu, Y. Dezhong
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引用次数: 5

Abstract

In order to obtain a sensitive parameter to discriminate the different stages of epilepsy, we studied pilocarpine-induced epileptic rat's ECoG and EHG by bispectrum analysis method based on the assumption that EEG is nonGaussian and nonlinear signal. In this paper, we proposed a model of EEG signals according to the parameter model stimulated by nonGaussian white noise to estimate the bispectrum of EEG. The results showed that the bispectrum analysis is sensitive to the epileptic and nonepileptic EEG. From these results, the quantified parameters presenting the features of epileptic EEG can be found, which could be new evidences to clinical monitoring and predicting of seizure.
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应用双谱分析研究癫痫大鼠脑电图
在假定脑电图是非高斯非线性信号的基础上,采用双谱分析方法对匹罗卡品诱发的癫痫大鼠脑电图和脑电图进行了研究,以期获得一个判别癫痫不同阶段的敏感参数。本文提出了一种基于非高斯白噪声刺激参数模型的脑电信号模型,用于估计脑电信号的双谱。结果表明,双谱分析对癫痫性和非癫痫性脑电图具有较好的敏感性。从这些结果中可以找到表征癫痫性脑电图特征的量化参数,为临床监测和预测癫痫发作提供新的依据。
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