{"title":"CHAPTER 4. Flow Chemistry in Drug Discovery","authors":"J. Alcázar, A. Hoz, Á. Díaz‐Ortiz","doi":"10.1039/9781788016131-00053","DOIUrl":null,"url":null,"abstract":"This chapter provides an overview of the use of flow chemistry in drug discovery settings, first introducing the green characteristics of flow chemistry and then describing the drug discovery process and how both worlds can be matched. Examples are provided that cover all stages of drug discovery, from the identification of the initial hits to the preparation of Active Pharmaceutical Ingredients. The automation and integration of new green technologies are also reported.","PeriodicalId":202204,"journal":{"name":"Green Chemistry Series","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Green Chemistry Series","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/9781788016131-00053","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
This chapter provides an overview of the use of flow chemistry in drug discovery settings, first introducing the green characteristics of flow chemistry and then describing the drug discovery process and how both worlds can be matched. Examples are provided that cover all stages of drug discovery, from the identification of the initial hits to the preparation of Active Pharmaceutical Ingredients. The automation and integration of new green technologies are also reported.
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