Biomedical micro and nanotechnology: From lab-on-chip to building systems with cells

U. Hassan, P. Bajaj, G. Damhorst, R. Bashir
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引用次数: 8

Abstract

Biomedical applications of micro and nanotechnology hold tremendous promise in diagnostics, therapeutic, and tissue engineering. Lab on chip devices can be used for the rapid and sensitive detection of biological entities including cells, bacteria, proteins and DNA. These microfluidic devices can provide for the sensitive and selective detection of CD4+ T cells for detection of HIV/AIDs for global health at point of care. Significant opportunities exist for rapid point-of-care detection of nucleic acid molecules from bacterial or viral agents of infection, for food borne pathogens. Tremendous opportunities exist in the development of cell-based bio-actuators, autonomous biological micro robots and cellular machines for a wide range of applications.
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微生物医学和纳米技术:从芯片实验室到细胞构建系统
微纳米技术在生物医学上的应用在诊断、治疗和组织工程方面有着巨大的前景。芯片实验室设备可用于快速、灵敏地检测生物实体,包括细胞、细菌、蛋白质和DNA。这些微流控装置可以提供CD4+ T细胞的敏感和选择性检测,用于在护理点检测艾滋病毒/艾滋病。对于食源性病原体,存在着对细菌或病毒感染源的核酸分子进行即时快速检测的重要机会。基于细胞的生物致动器、自主生物微机器人和细胞机器具有广阔的应用前景。
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