Importance of absolute eosinophil count in covid-19 patients

Kunal Gaur, S. Natarajan, Mohini Gupta
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Abstract

Coronavirus 2 (SARS-CoV-2) has created worldwide healthcare problems and strained health resources. Reduced eosinophil levels are one of the unique discoveries that have been discovered in COVID 19 recently. The goal of this study is to establish the association between the mortality in COVID-19 with eosinopenia by retrospectively analysing data from fifty COVID-19 patients with varying illness severity, including moderate, severe, and critically ill. Fifty patients taken from Sree Balaji Medical College and Hospital, of which twenty five critically ill patients and twenty-five having moderate to severe COVID-19 infection at hospital admission were enrolled. After being admitted to the hospital, information on the patient's medical history, clinical symptoms, CT severity score, and outcomes were taken from their medical records. The study concluded that Compared to individuals with moderate and severe disorders, critical illness patients' eosinophil levels were much lower. Eosinophil levels gradually decreasing was found to be a separate factor which has been associated with mortality. Patients with COVID-19 who have eosinopenia have a considerably higher mortality rate. These values can be obtained by simple means such as obtaining peripheral blood, so this is an easy and an effective indicator in monitoring these patients.
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嗜酸性粒细胞绝对计数在covid-19患者中的重要性
冠状病毒2 (SARS-CoV-2)造成了全球性的卫生保健问题和紧张的卫生资源。嗜酸性粒细胞水平降低是最近在COVID - 19中发现的独特发现之一。本研究的目的是通过回顾性分析50例不同疾病严重程度(包括中度、重度和危重症)的COVID-19患者的数据,建立COVID-19死亡率与红细胞减少之间的关联。选取了来自Sree Balaji医学院和医院的50例患者,其中25例危重患者和25例入院时患有中至重度COVID-19感染的患者。入院后,从患者的医疗记录中获取患者的病史、临床症状、CT严重程度评分和结果等信息。研究表明,与中度和重度疾病患者相比,危重症患者的嗜酸性粒细胞水平要低得多。嗜酸性粒细胞水平逐渐下降被发现是与死亡率相关的一个单独因素。患有红细胞减少症的COVID-19患者死亡率要高得多。这些数值可以通过采集外周血等简单的方法获得,因此这是监测这些患者的一种简便有效的指标。
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