Hepatitis B Vaccination Coverage, HBS-Ab Level and its Related Factors among Dentistry and Medical Students

Sajjad Shamloo, P. Davoodian, K. Nematpour, M. Hassani Azad, H. Dadvand
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Abstract

Background: In Iran, hepatitis B vaccination has been routinely performed for infants since 1993. This vaccination has also been suggested for individuals at risk. Recently, with the birth of children in 1993 and later to the age of entry to the university, assuming they were vaccinated against hepatitis B at birth, the issue of tracking the immunity of these students has been obscured or neglected. Moreover, the entry of some individuals born before 1993 to the university who have not been immunized against this disease in childhood, has made this issue more complicated. Objectives: The aim of this study was to investigate Hepatitis B Vaccination Coverage, HBS-Ab level and its related factors among dentistry and medical students. Methods: This study was a cross-sectional study performed through providing a checklist and serological tests. After obtaining written consent from the students, the information of 300 students were entered into SPSS software, version 16.0, and analyzed using descriptive statistics. Kruskal-Wallis and Mann-Whitney U tests were used and P<0.05 was considered as statistically significant. Results: Of the 300 students, 55%, 28.7%, and 16.3% had weak, medium, and good HBS-Ab titer with rates of less than 10, 10 to 100, and more than 100, respectively, moreover, the mean HBS-Ab titer was significantly different between different immune groups (Weak, Medium, and Good) (P = 0.000) (Write P<0.001 instead of P = 0.000). Vaccination coverage was at a very low level so that only 6.3% of the subjects completed the hepatitis B vaccination in the past 1 to 5 years (when entering university). the mean HBS-Ab titer was significantly correlated with the time elapsed since the last vaccination (P<0.05) (It was better to write the exact P values). The immunity level among the married individuals and clinical students was significantly higher compared to the single individuals and preclinical students, respectively (P<0.05). Conclusions: Considering the low level of vaccination coverage among the students of Hormozgan University of Medical Sciences (6.3%) compared with other universities, it is better to design a program that will allow all students enrolled in such fields to receive hepatitis B vaccination when entering the university.
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牙医学生乙肝疫苗接种率、HBS-Ab水平及其影响因素
背景:在伊朗,自1993年以来,对婴儿进行了常规的乙肝疫苗接种。也建议高危人群接种这种疫苗。最近,随着1993年孩子的出生,以及后来进入大学的年龄,假设他们在出生时接种了乙型肝炎疫苗,跟踪这些学生免疫的问题被掩盖或忽视了。此外,1993年以前出生的一些人进入大学,他们在童年时期没有接种过这种疾病的疫苗,使这个问题更加复杂。目的:调查牙科和医科学生乙型肝炎疫苗接种率、乙型肝炎抗体水平及其相关因素。方法:本研究是一项横断面研究,通过提供检查表和血清学测试来完成。在征得学生的书面同意后,将300名学生的信息输入SPSS软件16.0版,采用描述性统计方法进行分析。采用Kruskal-Wallis检验和Mann-Whitney U检验,P<0.05为差异有统计学意义。结果:300名学生中,弱、中、好、弱滴度比例分别为55%、28.7%、16.3%,小于10、10 ~ 100、大于100,且不同免疫组(弱、中、好)的平均HBS-Ab滴度差异有统计学意义(P = 0.000) (P <0.001,而非P = 0.000)。疫苗接种覆盖率很低,在过去1至5年(进入大学时),只有6.3%的受试者完成了乙型肝炎疫苗接种。平均HBS-Ab滴度与最后一次接种时间显著相关(P<0.05)(最好写准确的P值)。已婚大学生和临床生的免疫水平均显著高于单身大学生和临床前大学生(P<0.05)。结论:考虑到霍尔木兹甘医科大学学生乙肝疫苗接种率较低(6.3%),与其他高校相比,最好设计乙肝疫苗接种率方案,使该专业的学生在入学时都能接种乙肝疫苗。
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