Quantitative Spatial Frequency Domain Fluorescence Imaging for Surgical Guidance: Fluorophore Concentration Estimation in Pre-Clinical Cancer Models

Natalie Won, Josephine La Macchia, Anjola Adewale, Mandolin L Bartling, Esmat Najjar, B. Wilson, Jonathan C. Irish, M. Daly
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Abstract

Image quantification of fluorophore concentration based on phase-shifted sinusoidal patterns projected onto the surgical field. Results analyzed in an oral cancer mouse model and optical phantoms derived from tongue cancer patients.
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