Medication Use Status and Its Related Factors among Older Adults in Kerman, Iran

Rezvan Davari, Mohammad Ali Morowatisharifabad, Alireza Beigomi, Sara Jam Barsang
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Abstract

Introduction: Older adults are the largest group of medication users in each society. Since medications act differently in seniors compared with younger patients, great considerations are required regarding the effects and side effects of medications in the older adults. The present study aimed to determine the status of medication use and its related factors among older adults in Kerman city, Iran.   Methods: In the cross-sectional study, 388 seniors were selected using multistage cluster sampling from the population covered by comprehensive health centers in Kerman in 2021. Demographic information questions (age, gender, education level, marital status, life status, substance abuse, income, and health insurance status), a question regarding medication usage status and a question regarding disease that the elderly are currently suffering from, Montreal Cognitive Assessment Questionnaire, Geriatric Depression Scale, and Sleep Disorder Questionnaire were used for data collection. The data were analyzed using SPSS software by running Chi-square and multiple logistic regression tests.   Results: The average number of medications used per day was 4.59 and 53.5% of the participants used five or more medications concomitantly. Antihypertensive medications had the highest prevalence (64.3%) followed by anti-hyperlipidemic (43.6%) and Supplements (41.3%). A significant correlation was found between the participants' frequency of medication use and their gender, income, primary insomnia, and cognitive impairment (p < 0.001). However, medication use had no significant association with the senior's age, marital status, education level, living status, substance abuse, and health insurance (p < 0.05). The risk of polypharmacy was 2.15 times higher in the elderly women than men (p = 0.001) and 0.45 times higher in participants with depression than non-depressed seniors (p = 0.011).   Conclusion: The high prevalence of polypharmacy indicates an unfavorable status of medication use among older adults in Kerman. So, authorities are required to provide educational information about polypharmacy to aged groups.
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伊朗克尔曼地区老年人药物使用状况及其相关因素
在每个社会中,老年人是最大的药物使用者群体。由于药物在老年患者中的作用与年轻患者不同,因此需要对药物在老年患者中的作用和副作用进行大量的考虑。本研究旨在了解伊朗克尔曼市老年人的药物使用状况及其相关因素。方法:采用横断面研究方法,采用多阶段整群抽样方法,从2021年克尔曼市综合卫生中心覆盖的人群中抽取388名老年人。人口统计信息问题(年龄、性别、受教育程度、婚姻状况、生活状况、药物滥用、收入和健康保险状况)、药物使用状况问题和老年人目前患有的疾病问题、蒙特利尔认知评估问卷、老年抑郁量表和睡眠障碍问卷进行数据收集。采用SPSS软件进行χ 2检验和多元logistic回归检验。结果:平均每天使用药物4.59种,53.5%的参与者同时使用5种及以上药物。降压药患病率最高(64.3%),其次是抗高脂血药(43.6%)和补充剂(41.3%)。受试者的用药频率与性别、收入、原发性失眠和认知障碍之间存在显著相关性(p < 0.001)。用药与老年人年龄、婚姻状况、文化程度、生活状况、药物滥用、健康保险无显著相关(p < 0.05)。老年女性服用多种药物的风险比男性高2.15倍(p = 0.001),抑郁症患者比非抑郁症老年人高0.45倍(p = 0.011)。结论:多种用药的高流行率表明克尔曼老年人用药状况不佳。因此,当局需要向老年人提供有关多种药物的教育信息。
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