The Usefulness of Common IVY (Hedera helix L.) Extracts Against Bacterial and Fungal Pathogens Found in Local Hospitals

K. Rehman, M. Hamayun, Tabassum Yaseen, Z. Butt, Gulzad Ahmad, S. Wali
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引用次数: 1

Abstract

The current study was carried out to highlights the antibacterial and antifungal activity of Hedera helix L. by using its different fractions. Both activities were carried out under agar well diffusion method, while for fractions obtaining the cold maceration method was followed which were tested against four fungal species including Fusarium oxysporum, Aspergillus flavors, P. pallidum and Alternaria alternate and four bacterial strains, Staphylococcus aureus, Streptococcus mutans, Serratia marcescens and Methicillin resistance, Staphylococcus aureus. The fractions which were extracted from the Hedera helix shown different zone of inhibition (ZOI) against both the fungal and bacterial strains. Chloroform and n-hexane extracted samples showed the highest antifungal activity against Polyspondylium pallidum with complete inhibition zone and the least activity was shown by an aqueous fraction. In the antibacterial activity, the crude methanolic extracts have shown the highest inhibition zone (46-57%) against the selected bacterial strains, while the lowest activity was reported from aqueous fractions (21-26%). The other fractions moderately inhibit the growth of the selected strains but were significant.  
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常青藤(Hedera helix L.)的用途在地方医院发现的抗细菌和真菌病原体提取物
本研究通过对其不同组分的研究,揭示了其抗菌和抗真菌活性。两种活性均采用琼脂孔扩散法进行,对冷浸渍法获得的组分分别进行了尖孢镰刀菌、风味曲霉、苍白卟啉卟啉菌和交替孢霉4种真菌和金黄色葡萄球菌、变形链球菌、粘质沙雷菌和耐甲氧西林金黄色葡萄球菌4种细菌的抑菌试验。对真菌和细菌均有不同的抑制区(ZOI)。氯仿和正己烷提取物对苍白多脊柱菌的抑菌活性最高,具有完整的抑菌带,而水溶液提取物的抑菌活性最低。在抑菌活性方面,粗甲醇提取物对所选菌株的抑菌活性最高(46 ~ 57%),而水溶液提取物的抑菌活性最低(21 ~ 26%)。其他部分对所选菌株的生长有中等抑制作用,但抑菌效果显著。
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