The Role of CT-Based Radiomics in Precise Imaging of Renal Cancer

M. Ligero, K. Bernatowicz, R. Perez-Lopez
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Abstract

The application of advanced computational analysis to medical imaging opens a plethora of opportunities in the field of radiology, allowing for more accurate tissue characterization and, eventually, advancing towards precision medicine through imaging biomarkers. In this review, we briefly introduce the methodology for radiomics analysis and the main challenges for implementation of radiomics-based tools in clinical practice. Based on systematic review of published studies, we also summarize here the main advances regarding CT-based radiomics applications in renal cancer with regards to tumor characterization (diagnosis, grading, prognosis), gene expression prediction (radiogenomics) and response evaluation.
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基于ct的放射组学在肾癌精确成像中的作用
先进的计算分析在医学成像中的应用为放射学领域提供了大量的机会,允许更准确的组织表征,并最终通过成像生物标志物向精密医学迈进。在这篇综述中,我们简要介绍了放射组学分析的方法和在临床实践中实施基于放射组学的工具的主要挑战。在系统回顾已发表研究的基础上,我们也总结了基于ct的放射组学在肾癌肿瘤表征(诊断、分级、预后)、基因表达预测(放射基因组学)和反应评估方面的主要进展。
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