COVID-19 Infection Presenting as Acute Onset Focal Status Epilepticus in a Nine Year Old Boy

Jeffrey Swarz, S. Daily, E. Niemi, Samuel G. Hilbert, H. Ibrahim, Daniela Rauch, J. Gaitanis
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Abstract

Estimates suggest children currently account for 1%-5% of diagnosed COVID-19 cases [1,2]. Available literature focusing on children is limited in comparison to adults but suggests the clinical spectrum of illness in the pediatric population associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes coronavirus disease 2019 (COVID-19) is distinct from and broader than that in the adults. The most frequently reported symptoms in adults with COVID-19 include fever, dry cough, fatigue, and in severe cases dyspnea is common [3]. Children, when symptomatic, also present with fever and cough, but a significant proportion present with atypical symptoms such as vomiting and diarrhea [4,5]. A large proportion of COVID-19 positive children are asymptomatic or have mild cases of disease [6,7]. This difference in presentation and severity may lead to underdiagnosis in children facilitating spread of the disease [8]. This report documents the first reported case of a COVID-19 positive child presenting with focal status epilepticus.
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一名9岁男孩的COVID-19感染表现为急性发作局灶性癫痫持续状态
据估计,目前儿童占COVID-19确诊病例的1%-5%[1,2]。与成人相比,针对儿童的现有文献有限,但表明与导致2019冠状病毒病(COVID-19)的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)相关的儿科人群的临床疾病谱与成人不同,而且比成人更广泛。成人COVID-19中最常见的报告症状包括发烧、干咳、疲劳,严重者常见呼吸困难[3]。儿童在出现症状时也会出现发烧和咳嗽,但相当大比例的儿童会出现呕吐和腹泻等非典型症状[4,5]。很大一部分COVID-19阳性儿童无症状或病情轻微[6,7]。这种表现和严重程度的差异可能导致儿童诊断不足,从而促进疾病的传播[8]。本报告记录了首例报告的COVID-19阳性儿童出现局灶性癫痫持续状态的病例。
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