The Impact of Pulse Electric Field Treatment and Selected Bioactive Compound Extract toward Anticancer Treatment

Abstract

Pulse electric field were induced by using electroporation (EP) method which controlling the cell function to induce the substance into the cell by an opening pores on the cell membrane. In medical field, this approach has been applied widely, especially in cell studies. This paper focus on high voltage pulse electric field (HVPG) applied on MCF-7 cell (Human Breast cancer cell) to investigate the electroporation process (500, 1000, 1500 and 2000 V/cm) with additional of bioactive compound extract, in order to look at the effectiveness of these two method through an anti-proliferation properties of MCF-7 cell. Thus, this findings will be used in cell cancer treatment with a stimulator which is the electric field to enhance the absorption of the bioactive compound extract into the cells. These methods will contribute towards understanding the cell cancer treatment that will lead towards an incentive technique for cancer cell treatment.