On the way to strict glycemic control for hemodialysis patients

Abstract

Diabetes mellitus is a major risk factor for building chronic kidney disease. With the increasing number of diagnosed diabetic patients the number of related kidney replacement therapies will increase. The insulin is small enough to be filtered out during hemodialysis, therefore it is partially removed during treatment. The aim of this paper is to give a proposal on how to create an automatic control of insulin dosage during hemodialysis treatment with specific respect on insulin clearance. Our expectation would be that such a control (thanks to the regular execution of hemodialysis treatment) would slow down the degradation in kidney functionalities thus prolonging patient life and improving life quality.