[Contrast sensitivity and diabetes].

J P Nordmann, A Guigui, L Laroche, P Denis, H Saraux
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Abstract

Contrast sensitivity has been assessed in 24 diabetic patients in order to test the hypothesis that contrast sensitivity is impaired in the early stages of diabetes mellitus. All patients had 20/20 vision. Some evidence of visual dysfunction was observed in 33% of the diabetics with no retinopathy and 83% of the 6 patients with retinopathy when compared to 48 age-matched controls. Contrast sensitivity was mainly reduced in the mid-range spatial frequencies and correlated with the degree of retinopathy. The accurate assessment of visual dysfunction in diabetes is very important, as new drugs (i.e. aldose reductase inhibitors) are currently under evaluation.

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[对比敏感性和糖尿病]。
我们对24例糖尿病患者的对比敏感度进行了评估,以检验对比敏感度在糖尿病早期受损的假设。所有患者视力均为20/20。与48名年龄匹配的对照组相比,33%的无视网膜病变的糖尿病患者和83%的6名视网膜病变患者观察到一些视力障碍的证据。对比敏感度主要在中频空间频率降低,且与视网膜病变程度相关。准确评估糖尿病患者的视觉功能障碍非常重要,因为目前正在评估新的药物(如醛糖还原酶抑制剂)。
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