Clinical case report: Chronic kidney disease and ESKD (End stage kidney disease)

Javaid Ahmad Mir, Onaisa Aalia Mushtaq, Bushra Mushtaq
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Abstract

Chronic kidney disease include fibrosis, loss of renal cells and infiltration of renal tissue by monocytes and macrophages. The pathophysiology may include protein uria, hypoxia and excessive angiotensive II production. Hypoxia also contributes to disease progression. The disease has a vast number of clinical manifestations which include abnormalities in laboratory tests, hypertension, fatigue and poor appetite. There are five stages of CKD and in stage 5 the full blown clinical manifestations of end -stage renal disease are evident.Medical this disease can be managed by:1. Controlling blood pressure. 2. Managing blood glucose level to maintain HbA1c below 7%. 3. Managing hyperlipidemia with diet and cholesterol lowering drugs. 3. Managing and treating emerging manifestations of renal failure. 4. Prepare clients for renal replacement therapy when necessary. Patients condition (general condition) was fair, GCS 15/15,but had ineffective coping strategies, he was very much worried about his condition & renal transplant. He was not satisfied about the treatment received. Doctors have planned to discharge him till they arrange a donor for kidney.
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慢性肾病伴终末期肾病ESKD临床报告
慢性肾脏疾病包括纤维化、肾细胞丧失和肾组织被单核细胞和巨噬细胞浸润。病理生理可能包括蛋白尿、缺氧和血管紧张II生成过多。缺氧也会导致疾病进展。该病有多种临床表现,包括实验室检查异常、高血压、疲劳和食欲不振。CKD有五个阶段,在第5阶段,终末期肾脏疾病的全面临床表现是明显的。医学上对本病的治疗方法有:控制血压。2. 控制血糖水平,维持HbA1c低于7%。3.通过饮食和降胆固醇药物控制高脂血症。3.管理和治疗肾衰的新表现。4. 必要时为病人准备肾脏替代治疗。患者病情(一般情况)尚可,GCS 15/15,但应对策略无效,对自己的病情及肾移植非常担心。他对所受的待遇不满意。医生计划让他出院,直到找到肾脏捐赠者。
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