Identification of exon location applying kaiser window and DFT techniques

Lopamudra Das, J. Das, S. Nanda
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引用次数: 6

Abstract

Recognition of exons in a Eukaryotic cell is an indispensable problem in Genomic Signal Processing field to determine parts of DNA sequences that carry protein information. A new hybrid approach using Kaiser window and Discrete Fourier Transform has been presented in this paper for exon location detection. Furthermore various numerical mapping schemes have been modeled and tested for locating the protein coding regions (EXONS) by exploiting the Period-3 property of the exonic regions. The resulting power spectrum density curve proves the efficacy of the algorithm. The proposed approach is simple with less computational complexity that makes it easier to be implemented on a hardware platform. Moreover the proposed approach also reveals significant results in comparison to the other existing techniques.
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应用kaiser窗和DFT技术识别外显子位置
真核细胞外显子识别是基因组信号处理领域中确定携带蛋白质信息的DNA序列的一个不可缺少的问题。本文提出了一种利用Kaiser窗和离散傅立叶变换进行外显子位置检测的新方法。此外,通过利用外显子区域的周期-3特性,模拟和测试了各种数值映射方案来定位蛋白质编码区(外显子)。得到的功率谱密度曲线证明了算法的有效性。该方法简单,计算复杂度低,易于在硬件平台上实现。此外,与其他现有技术相比,所提出的方法也显示出显著的结果。
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