Biological and histological variability of breast cancer

M. Cabrera, Celeste Aparicio de Real
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Abstract

Introduction: breast cancer in women is one of the most studied malignancies. Its risk factors are well identified and it´s one of the pathologies with more classifications throughout the history of Medicine. Objectives: to describe the clinical characteristics of breast cancer in the San Pablo Hospital (Asunción, Paraguay) the period of 2016-2017. Methodology: retrospective descriptive observational design of medical records revision of patients with histological confirmation of breast cancer from San Pablo Hospital (Asunción, Paraguay) in the period of 2016-2017. Results: 75 cases were included. The mean age was 52 ± 11 years. The most frequent histological type was the infiltrating ductal with a moderate degree of differentiation at the time of diagnosis. The clinical stage at the time of the most frequent diagnosis was stage II and the luminal biological type A was the most frequent. The treatment established in most cases were modified radical mastectomy. Conclusions: the most frequent breast cancer was infiltrating ductal, stage II. Modified radical mastectomy was the most used treatment.
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乳腺癌的生物学和组织学变异
女性乳腺癌是研究最多的恶性肿瘤之一。其危险因素已被很好地识别,并且在整个医学史上,它是具有更多分类的病理之一。目的:描述2016-2017年巴拉圭圣巴勃罗医院(Asunción)乳腺癌的临床特征。方法:采用回顾性描述性观察设计,对2016-2017年巴拉圭San Pablo医院(Asunción)组织学证实的乳腺癌患者的病历进行修订。结果:共纳入75例。平均年龄52±11岁。最常见的组织学类型是浸润性导管,诊断时分化程度中等。诊断时最常见的临床分期为II期,最常见的是腔内生物学型A型。大多数病例的治疗方法是改良根治性乳房切除术。结论:乳腺癌以浸润性导管居多,为II期。改良根治性乳房切除术是最常用的治疗方法。
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