Reaction strategies for synthesis of imidazole derivatives: a review

S. Atanasova-Stamova, S. Georgieva, M. Georgieva
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引用次数: 5

Abstract

The development of a methodical directional synthesis of complex organic molecules with the aim of obtaining the physiologically active substance with selective action takes a central position in modern synthetic organic chemistry. Imidazole derivatives are a key component in great many bioactive compounds of both natural and synthetic origin. Ðœany scientists in the field of pharmaceutical chemistry and pharmacology have been attracted to them in recent years. This is because of the exceptional chemical properties and biological activities that they demonstrate. It is a big challenge for the scientists to modify and synthesize new imidazole derivatives.
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咪唑衍生物合成的反应策略综述
以获得具有选择性作用的生理活性物质为目标的复杂有机分子的有系统定向合成的发展在现代合成有机化学中占有中心地位。咪唑衍生物是许多天然和人工合成的生物活性化合物的关键成分。Ðœany近年来吸引了药物化学和药理学领域的科学家。这是因为它们具有特殊的化学性质和生物活性。如何修饰和合成新的咪唑衍生物对科学家来说是一个巨大的挑战。
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