A statistical approach to transmission image reconstruction from ring source calibration measurements in PET

E. Mumcuoglu, R. Leahy, S. Cherry
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引用次数: 17

Abstract

The problem of reconstructing a transmission attenuation image is addressed. The estimation procedure is based on a Bayesian formulation incorporating a Poisson likelihood model that includes scatter for the transmission data and a Markov random field prior. The results obtained using this approach result in improved accuracy in computing the ACFs (attenuation correction factors). A transmission image is also useful for reconstructing anatomical landmarks for use in cross-modality registration. A third advantage of reconstruction of the transmission image is that, if the patient moves between the transmission and one or more emission scans, the reconstructed transmission image can be used to generate ACFs for any new position. Several candidate optimization techniques are investigated, and the quantitative accuracy of the reconstructed images is evaluated.<>
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PET环源标定传输图像重建的统计方法
讨论了传输衰减图像的重建问题。估计过程基于贝叶斯公式,该公式结合了泊松似然模型,其中包括传输数据的散点和马尔可夫随机场先验。使用这种方法获得的结果提高了计算ACFs(衰减校正因子)的精度。传输图像对于重建用于跨模态配准的解剖标志也很有用。传输图像重建的第三个优点是,如果患者在传输和一个或多个发射扫描之间移动,则重建的传输图像可用于生成任何新位置的ACFs。研究了几种候选优化技术,并对重建图像的定量精度进行了评价
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