Evaluation of Fine Needle Aspiration Cytology in Diagnosis of Salivary Gland Lesions: A Teaching Hospital Based Study

Santanu Kumar, W. Ahmad
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Abstract

Background: FNAC is a cytodiagnostic method based on the morphological findings of individual cells, group of cells, and microparticles of tissue, acquired using a needle. The role of FNAC for the diagnosis of salivary gland masses is well documented. The traditional open biopsy is no longer justified because of the risk of tumor spillage and damage to the facial nerve.Subjects and Methods:FNAC procedure was explained to the patient and patient was placed in a comfortable position. They were then subjected to fine needle aspiration cytology. Aspirations were carried out with 21 or 22 gauge needles of varying lengths with 10 ml syringes in a syringe holder after careful clinical examination of the lesion.Results:Chronic sialadenitis was the most common non-neoplastic lesion (13.2%) followed by cystic lesions (5.3%), acute on chronic sialadenitis (3.9%) and chronic granulomatous inflammation (2.6%). Pleomorphic adenoma (57.9%) was the most common benign neoplasm. Warthin’stumour accounted for (6.6%). Mucoepidermoid carcinoma was the most common malignant lesion (5.3%) followed by acinic cell carcinoma (1.3%), carcinoma-ex pleomorphic adenoma (1.3%) and adenoid cystic carcinoma (2.6%).Conclusion: Fine needle aspiration cytology of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions.
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基于教学医院的细针穿刺细胞学诊断唾液腺病变的研究
背景:FNAC是一种基于单个细胞、细胞群和组织微粒形态学结果的细胞诊断方法,使用针刺获得。FNAC在涎腺肿块诊断中的作用已得到充分证实。由于存在肿瘤外溢和面神经损伤的风险,传统的开放性活检已不再适用。对象和方法:向患者解释FNAC手术程序,并将患者置于舒适体位。然后进行细针抽吸细胞学检查。在仔细的临床检查病变后,用不同长度的21或22号针头和10毫升注射器在注射器支架中进行吸气。结果:慢性涎腺炎是最常见的非肿瘤性病变(13.2%),其次是囊性病变(5.3%)、急性慢性涎腺炎(3.9%)和慢性肉芽肿性炎症(2.6%)。多形性腺瘤(57.9%)是最常见的良性肿瘤。沃辛顿占6.6%。粘液表皮样癌是最常见的恶性病变(5.3%),其次是腺泡细胞癌(1.3%)、癌前多形性腺瘤(1.3%)和腺样囊性癌(2.6%)。结论:涎腺细针穿刺细胞学检查是一种安全可靠的涎腺病变初步诊断技术。虽然,在细胞学上预测特定病变时遇到了局限性,特别是在处理囊性病变和一些恶性病变时。
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