Evaluation of Microbiological Contamination of Some Selected Syrups and Suspentions Solid in Katsina Metropolis

Abstract

Presented study attempted to evaluate the Microbiological contamination of some selected syrups and suspensions sold in Katsina metropolis. This study was conducted in Biological sciences laboratory Al-qalam University Katsina between the months of November 2021 to January 2022. Eighteen different types of oral liquid drugs (9 syrups and 9 suspensions) manufactured in different pharmaceutical industries of Nigeria were microbiologically examined using standard cultural and biochemical methods. All the samples were found to be contaminated with total viable bacteria and fungi with a maximum load of 103 cfu/ml among all samples were exceeded the United States Pharmacopeia (USP) limit (<102 cfu/ml). While the presences bacteria including; E.coli, Salmonella spp., Shigella spp., were found to be presences in almost all samples, (the former of E.coli in 11 syrups and suspension samples, the Salmonella spp. in 3 suspension samples and the Shigella spp. In 8 suspensions). Existence of microorganisms in the oral liquid samples might explain the treatment complicacy of the diseased children. A routine microbiological study of such drugs is thus suggested.