{"title":"A Nanosurface Microfluidic Device for Capture and Detection of Bacteria","authors":"Tamer AbdEIFatah, M. Jalali, S. Mahshid","doi":"10.1109/LSC.2018.8572083","DOIUrl":null,"url":null,"abstract":"Here we report on design, fabrication and implementation of a nanosurfac microfluidic device for efficient bacteria capture and optical detection. The device features simple design and ease of implementation. The principal of operation depends on the self-assembly of microparticles (polystyrene particles) at a pillar array region to form a Nano-filter for subsequent bacteria capture on gold nano/micro islands. The design was optimized using 2D COMSOL simulation. The device was fabricated using a single UV lithography step followed by electrodeposition of the gold structures and a subsequent step of polydimethylsiloxane (PDMS) bonding for device sealing. Lastly, the device was experimentally implemented using Escherichia coli (E. coli) bacteria showing efficient bacteria capturing performance.","PeriodicalId":254835,"journal":{"name":"2018 IEEE Life Sciences Conference (LSC)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 IEEE Life Sciences Conference (LSC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/LSC.2018.8572083","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Here we report on design, fabrication and implementation of a nanosurfac microfluidic device for efficient bacteria capture and optical detection. The device features simple design and ease of implementation. The principal of operation depends on the self-assembly of microparticles (polystyrene particles) at a pillar array region to form a Nano-filter for subsequent bacteria capture on gold nano/micro islands. The design was optimized using 2D COMSOL simulation. The device was fabricated using a single UV lithography step followed by electrodeposition of the gold structures and a subsequent step of polydimethylsiloxane (PDMS) bonding for device sealing. Lastly, the device was experimentally implemented using Escherichia coli (E. coli) bacteria showing efficient bacteria capturing performance.
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