[Elimination of the obturator reflex as a specific indication for dilute solutions of etidocaine. A study of the suitability of a local anesthetic for reflex elimination in the 3-in-1 block technic].

IF 1.9 Q2 POLITICAL SCIENCE Regional-Anaesthesie Pub Date : 1990-01-01
R Schwilick, K Weingärtner, G V Kissler, P Reinhold
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Abstract

Direct stimulation of the obturator nerve by the electroresectoscope during transurethral resection of tumors in lateral bladder regions is possible under regional or general anaesthesia without muscle relaxation. The resulting obturator reflex may lead to perforation of the bladder. Two different regional techniques can be used to interrupt the obturator reflex arc: (1) separate block of the obturator nerve; or (2) the "3-in-1 block" (Winnie). In the present study elimination of the obturator reflex was carried out by "3-in-1 block" with diluted solutions of etidocaine in 55 cases. Venous plasma levels of etidocaine were measured in 9 patients after application of etidocaine 0.5% (unilateral 30 ml and bilateral 60 ml). Samples were taken 10, 20, 30, 40, 60, and 120 min after the "3-in-1 block". RESULTS. The "3-in-1 block" with diluted etidocaine produced excellent motor block of the obturator nerve. Clinical side effects did not occur. Plasma peak levels reached 2.2 micrograms/ml; the protein binding rate was 85%-95%. DISCUSSION. Elimination of the obturator reflex is the only specific motor nerve block in anesthesia. Diluted etidocaine solutions seem to be adequate: irrespective the technique used for eliminating the reflex, diluted etidocaine produces a good effect and permits a dosage reduction compared with other local anesthetics. It is possible to block the obturator nerve bilaterally by "3-in-1 block" or unilaterally by "3-in-1 block" in combination with epidural analgesia within the recommended dose limits.

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[闭孔反射的消除作为稀释的伊蒂多卡因溶液的特殊指征。局部麻醉剂在三合一阻滞技术中用于消除反射的适宜性研究[j]。
在局部麻醉或全身麻醉不放松肌肉的情况下,经尿道膀胱外侧肿瘤切除术时,电切镜直接刺激闭孔神经是可行的。由此产生的闭孔反射可能导致膀胱穿孔。阻断闭孔反射弧可采用两种不同的局部技术:(1)单独阻断闭孔神经;(2)“三合一积木”(Winnie)。在本研究中,55例患者采用稀释的伊蒂多卡因溶液“三合一阻滞”法消除闭孔反射。9例患者应用0.5%伊地多卡因(单侧30 ml,双侧60 ml)后,测定静脉血浆中伊地多卡因水平。在“三合一块”后10、20、30、40、60和120分钟取样。结果。稀释的伊蒂多卡因“三合一阻滞”可产生良好的闭孔神经运动阻滞。未发生临床副作用。血浆峰值水平达到2.2微克/毫升;蛋白结合率为85% ~ 95%。讨论。闭孔反射的消除是麻醉中唯一的特异性运动神经阻滞。稀释的伊蒂多卡因溶液似乎是足够的:不管使用何种技术消除反射,稀释的伊蒂多卡因产生良好的效果,与其他局部麻醉剂相比,可以减少剂量。在推荐剂量范围内,可以采用双侧“三合一阻滞”或单侧“三合一阻滞”联合硬膜外镇痛来阻断闭孔神经。
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