An open label single arm prospective clinical study on Vatagajankusharasa with Pippali Churna and Manjishta Kwatha as Anupana in Viswachi (cervical spondylosis)

M. Gulfam, Totad Muttappa, Neelam Bisht, L VishnuM, Yadu Gopan
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Abstract

Background: Viswachi is one among the 80 Nanatmaja Vata Vyadhi. This disease affects the neck and upper extremities with the signs and symptoms like Ruk, Stambha, Toda, Bahu Karmakshaya. Vatagajankusha Rasa is a combination of Vyosha, Bhasmas, Vatsanabha, Karkatasringi, Haritaki etc. It has Vatakaphahara, Vikasi, Vyavayi, Rasayana etc. properties. It is said to be effective in treating Visawachi in 7 days if given along with Pippali Churna and Manjishta Kwatha. Aims and Objectives: To evaluate the efficacy of Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana in the management of Viswachi (Cervical spondylosis). Methodology: Among 35 registered patients, 30 completed the course of treatment. They were administered with Vatagajankusha Rasa 1 tablet (125 mg) after food with Anupana 3gm Pippali Churna and 15 ml Manjishta Kwatha twice daily (morning and evening) for a period of 7 days. Nominal and ordinal data were analysed using non parametric tests like McNemar and Wilcoxon’s signed rank tests respectively. Result: Assessment parameters like Ruk, Toda, Sthambha and Bahukarma Kshya. There was statistically significant improvement in the primary and secondary outcome measures (p less than 0.05 was observed). Conclusion: Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana is effective in the management of Viswachi (Cervical spondylosis).
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Vatagajankusharasa与Pippali Churna、Manjishta Kwatha联合治疗颈椎病的开放性单臂前瞻性临床研究
背景:Viswachi是80位Nanatmaja Vata Vyadhi之一。这种疾病影响颈部和上肢,体征和症状如Ruk, Stambha, Toda, Bahu Karmakshaya。Vatagajankusha Rasa是Vyosha, Bhasmas, Vatsanabha, Karkatasringi, Haritaki等的组合。它具有Vatakaphahara, Vikasi, Vyavayi, Rasayana等属性。据说,如果与Pippali Churna和Manjishta Kwatha一起服用,可以在7天内有效治疗Visawachi。目的和目的:评价Vatagajankusha Rasa联合Pippali Churna和Manjishta Kwatha作为Anupana治疗颈椎病的疗效。方法:35例患者中,30例完成疗程。进食后给予Vatagajankusha Rasa 1片(125 mg),同时给予Anupana 3gm Pippali Churna和Manjishta Kwatha 15 ml,每日两次(早晚),连续7天。分别使用McNemar和Wilcoxon的符号秩检验等非参数检验对标称和序数数据进行分析。结果:Ruk、Toda、shambha、Bahukarma Kshya等评价参数。主要和次要结局指标均有统计学显著改善(p < 0.05)。结论:Vatagajankusha Rasa联合Pippali Churna和Manjishta Kwatha作为Anupana治疗颈椎病是有效的。
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