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Assessment of relation between Dhatusarata and Dehabala w.s.r. to Harvard Step Test 哈佛阶跃检验对达图萨拉塔与德哈巴拉关系的评估
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.11
Amar Baliram Abhrange, Archana Amar Abhrange, S. S. Waghmare
The growth and existence of the human body is dependent on these seven Dhatus. These seven Dhatus are composed of five elements or Panchmahabhutas. Dhatu Sarata or Tissue excellence is a quality assessment of seven Dhatu. Examination of Dhatu Sarata is done at physical and psychological level. For determining the Dhatu Sarata, when the positive features are present above 75 %, it will be considered as best tissue quality (Uttam Sarata). When the positive features are present between 75 % and 25 %, it will be considered as moderate tissue quality (Madhyam Sarata). When positive features are present below 25 %, it will be labeled as poor tissue quality (Heen Sarata). The bodily movements which are meant for producing firmness and strength in the body are known as Vyayama or physical exercises. „Dehabala’ (Physical fitness) of subjects will be determined by Harvard step test. “Harvard Step Test” is a practical application of Ayurvedic Principal that “Bala should be measured by Vyamshakti” (Balam Vyayamshakty Parikshet). The person should be examined with reference to his capacity for exercise which is determined by one‟s ability to perform work. Therefore this study will estimate Dehabala and study the Dhatusarata and their association between them.
人体的生长和存在依赖于这七种状态。这七境是由五种元素或Panchmahabhutas组成的。Dhatu Sarata或组织卓越是对七个Dhatu的质量评估。对Dhatu Sarata的检查是在生理和心理层面进行的。在确定Dhatu Sarata时,当阳性特征高于75%时,将被认为是最佳组织质量(Uttam Sarata)。当阳性特征出现在75%到25%之间时,将被认为是中等组织质量(Madhyam Sarata)。当阳性特征低于25%时,将标记为组织质量差(Heen Sarata)。旨在增强身体强度和力量的身体运动被称为Vyayama或体育锻炼。”受试者的Dehabala(身体素质)将通过哈佛步测来确定。“哈佛步骤测试”是阿育吠陀原则“巴拉应该由Vyamshakti测量”(Balam Vyayamshakty Parikshet)的实际应用。对一个人的检查应该参照他的运动能力,而运动能力是由一个人的工作能力决定的。因此,本研究将对Dehabala和Dhatusarata进行估计,并研究它们之间的关系。
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引用次数: 0
A randomized, comparative, open clinical trial for evaluating the efficacy of PP/JLN/107/09-10 Syrup in the management of Functional Constipation 一项评价PP/JLN/107/09-10糖浆治疗功能性便秘疗效的随机、比较、开放临床试验
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.5
M. Ramadas, Padmanabha Rugvedi, P. Gupta, R. Rai, J. Sastry
Context: Functional constipation which has no underlying organic causes is difficult to be allopathic treatment for long term due to its side effects and undeniable effect, thus a natural balanced and compatible formulation needs to be validated. Objectives: Current study aimed to assess a poly-herbal formulation in management of functional constipation. Material and Methods: This study was 28 days, two armed, randomized, open labeled, prospective clinical study. 60 clinically confirmed cases of functional constipation patients randomized to receive orally either 2 teaspoonful of PP/JLN/107/09-10 Syrup or 1 teaspoonful of 5- 6 gm of Isabgol powder. Results were analyzed as per Rome II criteria and other associated symptoms like headache, acidity, belching, barborgysmy, flatulence and abdominal dis tension or bloating which are recorded on VAS score. Results: PP/JLN/107/09-10 scored over Isabgol on four out of six parameters of Rome II Criteria viz., frequency of bowel movement, straining at defecation, lumpy I har dstool formation, feeling of incomplete evacuation, feeling of ano-rectal blockage and manual maneuvers (p less than 0.001). Trial drugs showed comparable effects (p > 0.05) in reducing the mean scores of associated symptoms like headache, acidity, belching, borgorgysmy, flatulence and abdominal distension. However, trial drug was found to perform statistically significant result in more number of parameters in comparison to Isabgol. Conclusion: PP/JLN/107/09-10 was found to be effective and safe in reliving functional constipation.
背景:功能性便秘没有潜在的器质性原因,由于其副作用和不可否认的影响,很难长期进行对抗疗法治疗,因此需要验证天然平衡和相容的配方。目的:本研究旨在评估一种多草药制剂在治疗功能性便秘中的作用。材料与方法:本研究为期28天,双臂,随机,开放标记,前瞻性临床研究。将60例临床确诊的功能性便秘患者随机分为两组,口服PP/JLN/107/09-10糖浆2茶匙或伊莎贝尔粉5- 6 gm 1茶匙。结果根据Rome II标准和其他相关症状(如头痛、胃酸、打嗝、呕吐、胀气、腹部紧张或腹胀)进行分析,并记录在VAS评分中。结果:PP/JLN/107/ 9-10在罗马II标准的六个参数中,即排便频率,排便紧张,肿块性大便形成,不完全排便感,肛门直肠阻塞感和手动操作中的四个参数得分高于Isabgol (p < 0.001)。试验药物在减少头痛、胃酸、打嗝、贪食、肠胃胀气和腹胀等相关症状的平均评分方面显示出相当的效果(p > 0.05)。然而,与伊莎贝尔相比,试验药物在更多的参数上表现出统计学显著的结果。结论:PP/JLN/107/09-10治疗功能性便秘安全有效。
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引用次数: 0
Comparative clinical study of Alambushadi Churna and Dwipanchmuladya Tail Basti in the management of Amavata vis-a–vis Rheumatoid Arthritis Alambushadi Churna与Dwipanchmuladya Tail Basti治疗Amavata对类风湿关节炎的比较临床研究
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.3
Sunil Kumar1, J. Singh, O. Singh, Mukesh Kumar
In Ayurvedic text book, Amavata symptom is mentioned as swelling, joint pain, numbness, appetite loss, indigestion and fever. In Charaka Samhita and Sushruta Samhita, Amavata is mentioned as a syndrome called Vatavyadhi, a diverse group of symptoms that are organized according to the systemic and local manifestations of Vata Dosha. According to the Charaka Samhita of Vatavyadhi, when Vata affects the Asthi and Majja there is painful swelling and immobility of the joints. Hence clinical study is planned to evaluate effect of Alambushadi Churna and in the Management of Amavata for that 60 Patients having classical symptomatology of Amavata have been selected from Kayachikitsa OPD and IPD of Sir Sunder Lal Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi and divided in two groups. Results of study shows that the sign and symptoms e.g., Loss of appetite, Angamarda, Alasya etc. due to derangement of Aam are observed to be improved in by Alambushadi Churna oral dose compared to Methotrexate.
在阿育吠陀教科书中,阿玛瓦塔症状被提到为肿胀,关节疼痛,麻木,食欲不振,消化不良和发烧。在《Charaka Samhita》和《Sushruta Samhita》中,Amavata被称为一种称为Vatavyadhi的综合征,是根据Vata Dosha的系统和局部表现而组织的多种症状。根据《瓦塔瓦耶地经》,当瓦塔影响到阿斯提和Majja时,关节会出现疼痛的肿胀和不动。因此,临床研究计划评估Alambushadi Churna和Amavata管理的效果,从瓦拉纳西巴纳拉斯印度教大学医学研究所Sir Sunder Lal医院Kayachikitsa OPD和IPD中选择60名具有Amavata典型症状的患者,分为两组。研究结果表明,与甲氨蝶呤相比,口服Alambushadi Churna可改善因Aam紊乱引起的食欲不振、Angamarda、Alasya等体征和症状。
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引用次数: 0
A Biochemical Approach to Understand the Concept of Snigdha Guna of Ghee and Ruksha Guna of Terminalia arjuna on Behaviour of 3T3-L1 Cell Line with Respect to Adipocytic and Anti-Adipocytic Activity : In Vitro 从生物化学角度理解印度酥油古拿和阿婆芦沙古拿概念对3T3-L1细胞系体外增脂和抗增脂活性的影响
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.9
Ruchika Dighekar, Kiran A. Tawalare
Ayurvedic medicine is a system of traditional medicine native to India. Ayurveda is based on peculiar fundamental principles like Shatpadarth, Tridosha Theory, Panchamahabhuta Theory, Prakriti, Ojas, Dhatu, Mala, Agni, Manas, and Atma etc. The concepts of Ayurveda are expressed with Gunas. The increased elements are treated by opposite Guna. In support of the above concept, an experimental study on the 3T3-L1 cell line is carried out for examine the adipocytic and anti adipocytic activity of Snigdha and Ruksha Guna respectively. The results were assessed with the help of evaluation of sublethal concentration by using XTT assay and lipid assay. The aim of basic research in Ayurveda through bioscience is to explore scientific innovation and opportunities in fundamental concept of Ayurveda. Fundamental research needs to be done to highlight the concept of gurvadi guna through the in vitro study.
阿育吠陀医学是印度本土的传统医学体系。阿育吠陀是基于独特的基本原则,如Shatpadarth, Tridosha理论,Panchamahabhuta理论,Prakriti, Ojas, Dhatu, Mala, Agni, Manas和Atma等。阿育吠陀的概念是用Gunas来表达的。增加的元素由相反的Guna处理。为了支持上述概念,我们对3T3-L1细胞系进行了实验研究,分别检测了snigha和Ruksha Guna的脂肪细胞活性和抗脂肪细胞活性。采用XTT法和脂质法评价亚致死浓度。通过生物科学进行阿育吠陀基础研究的目的是探索阿育吠陀基本概念的科学创新和机会。基础研究需要通过体外研究来突出gurvadi guna的概念。
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引用次数: 0
Pharmaceutico-analytical study of Mayurpiccha Bhasma - An Ayurvedic preparation 阿育吠陀制剂马尤尔皮茶的药学分析研究
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.16
Gangaprasad R. Asore, Baban Rathod, Dipalee Thakur
Background: Mayurpiccha Bhasma is a classical Ayurvedic kalpa prepare from peacock feathers, which is commonly used for treatment of Vomiting, Hiccups, Respiratory illness etc. Method of preparation of Mayurpiccha Bhasma is mentioned in Siddhayog sangraha and Bhaishyajya Samhita. Material and Methods: Mayurpiccha Bhasma was prepared by procedure mentioned in Siddhayog sangraha i.e. Peacock feathers are burn on ghee flame and finished product was subjected to various Physico-chemical analysis like Moisture content, Ash value, Chemical components etc. Observations: Observations were noted while testing of finish product. Result and Conclusion: Various observations and reports of tests were noted.
背景:Mayurpiccha Bhasma是一种经典的阿育吠陀卡尔巴,由孔雀羽毛制成,通常用于治疗呕吐,打嗝,呼吸系统疾病等。在《悉达约圣典》和《巴希雅雅典籍》中提到了马尤匹查巴士马的制备方法。材料和方法:Mayurpiccha Bhasma是按照Siddhayog sangraha中提到的程序制备的,即孔雀羽毛在酥油火焰上燃烧,成品经过各种物理化学分析,如水分含量,灰分值,化学成分等。观察结果:成品测试时注意观察结果。结果和结论:注意到各种观察和报告的测试。
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引用次数: 0
Quality standards of Palasha Kshara Gritha with reference to different vessels 参考不同容器的Palasha Kshara Gritha质量标准
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.14
Seema Mb, H PampannaGouda, Ravindra Angadi
This article attempts to clear the dogma that exists in the preparation of Kshara Ghrita with reference to its critical final stage of Siddhi Laxanas. Palasha Kshara Ghrita (PKG) prepared from the Kshara of Palasha (Grewia asiatica) mentioned in Rasa Tarangini, which is indicated in the treatment of Granthi (tumor) is taken for the study. The present article is an extract of all the observations made during the pharmaceutical study of PKG. All these observations will be of great help when we go for large scale production. The study has tried to establish the ratios of Dravadravyas with Kshara, besides addressing the type of vessels appropriate in such preparations. After preparation of sample in different vessels, these were subjected to analytical study using relevant analytical parameters to find out any difference. During pharmaceutical process Copper vessel was found appropriate on the lines of pharmaceutical preparations. The analytical report of samples reveals no much difference in the parameter findings except pH of PKG 7.00, 9.91 and 9.46 in the vessels such as copper, iron and mud pot respectively. The particle size of Kshara was in between 429.7 to 667 nm under 15.00KV magnification 7.5 KX and EDAX report of Phalasha Kshara under 400 μm potassium Wt% 40.05 and Oxygen is Wt% 39.12. Under 50 μm potassium Wt% 48.91 and Oxygen Wt% 33.40. Under 70 μm potassium Wt% 27.90 and Oxygen Wt% 37.78. As per this study copper vesse l is found better for PKG than Iron and Mud pot for assessment of end process and also on analytical parameter.
这篇文章试图澄清存在于《迦勒格里塔》准备中的教条,参考其关键的最后阶段悉地拉散那。从Rasa Tarangini中提到的Palasha Kshara (Grewia asiatica)制备的Palasha Kshara Ghrita (PKG),用于治疗Granthi(肿瘤)。本文是对PKG在药物研究过程中所观察到的结果的总结,这些结果将对我们的大规模生产有很大的帮助。该研究试图建立陀罗梵与沙罗的比例,除了解决在这种准备中合适的容器类型。在不同的容器中制备样品后,使用相关的分析参数进行分析研究,找出其中的差异。在制药过程中,铜容器被发现适合于药物制剂的生产线。样品的分析报告显示,除了铜、铁、泥罐等容器中PKG的pH值分别为7.00、9.91、9.46外,各参数结果没有太大差异。在15.00KV放大倍率为7.5 KX的条件下,Kshara的粒径在429.7 ~ 667nm之间;在400 μm钾、氧条件下,Phalasha Kshara的EDAX报告为Wt% 40.05, Wt% 39.12。在50 μm以下,钾Wt% 48.91,氧Wt% 33.40。在70 μm以下,钾Wt% 27.90,氧Wt% 37.78。本研究发现,铜罐比铁罐和泥罐更适合用于PKG的末端工艺评价和分析参数。
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引用次数: 0
Pharmaceutical standardization of Palashakshara Palashakshara药品标准化
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.15
Ganapathi Rao I, Chandrakanth Halli, Subhod Kamthikar
Standardization of herbal drugs is essential to certify their quality and purity. Kshara (alkaline substance) of Palasha (Butea monosperma) is an important constituent in many Ayurvedic formulations, but its standard manufacturing process (SMP) is not attempted till date. This study is aimed to establish SMP for Palashakshara. In pharmaceutical process; generally, the sediments of ash obtained at the end of washes will be discarded. However, in the study, we attempted to wash the sediments repeatedly by adding water to extract more Kshara. Palasha was collected from the local area and authenticated. Kshara was prepared by following standard methods and the preliminary physicochemical profile was developed. It is observed that the ash yields Kshara even in the consecutive washes. First wash yielded 21.23% w/w Kshara, while the second and third washes yielded 9.38% w/w and 4.76% w/w, respectively. Repeated washes yield more Kshara. Hence, it is advocated to wash the ashes repeatedly. As the findings are encouraging, similar experiments can be extended to all other Kshara preparations.
草药标准化是保证其质量和纯度的必要条件。Palasha (Butea monosperma)的Kshara(碱性物质)是许多阿育吠陀配方的重要成分,但其标准制造工艺(SMP)直到今天还没有尝试。本研究旨在建立帕拉沙克沙拉的SMP。在制药过程中;一般来说,在洗涤结束时获得的灰分沉积物将被丢弃。然而,在研究中,我们试图通过加水来反复洗涤沉积物,以提取更多的Kshara。帕拉沙是从当地收集并鉴定的。按照标准方法制备了Kshara,并对其进行了初步的理化分析。可以观察到,即使在连续洗涤中,灰分仍产生Kshara。第一次洗涤产生21.23% w/w Kshara,而第二次和第三次洗涤分别产生9.38%和4.76% w/w。反复洗涤产生更多的Kshara。因此,提倡反复清洗骨灰。由于研究结果令人鼓舞,类似的实验可以扩展到所有其他Kshara制剂。
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引用次数: 0
Antibacterial effectiveness of natural products alone and in combination with Calcium Hydroxide as Intracanal Medicaments : An In-Vitro Microbiological Study 天然产物单独和与氢氧化钙联合作为肛门内药物的抗菌效果:一项体外微生物学研究
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.10
Abhilasha Bhawalkar, S. Gulati, Sanjyot A Mulay, R. Shetty
Major objective of root canal treatment is disinfection of the root canal system and elimination of microbiota. Various intracanal medicaments as an adjunct to mechanical disinection and irrigation have been used but due to the harmful effects of the commercially available agents, a need for natural alternatives is felt over the time. This in-vitro study aims to evaluate the antibacterial effectiveness of natural agents Septillin and Aloe vera with Calcium hydroxide and without Calcium hydroxide on the Streptococcus mitis, E. Faecalis and Candida albicans using agar well diffusion method. The antibacterial activity was assessed by the diameter of zone of inhibition seen as clear zone around the wells. The study showed that Septillin in combination with Calcium hydroxide and alone showed considerable antimicrobial activity against Streptococcus mitis, Enterococcus faecalis and Candida albicans where as Aloe vera with Calcium hydroxide showed to be mildly effective against all three but not as effective as Septillin and Calcium hydroxide when tested alone.
根管治疗的主要目的是消毒根管系统和消除微生物群。作为机械消毒和冲洗的辅助手段,已经使用了各种肛管内药物,但由于市售药物的有害影响,随着时间的推移,人们感到需要天然替代品。本实验采用琼脂孔扩散法,比较天然药物Septillin和芦荟加氢氧化钙和不加氢氧化钙对霉菌链球菌、粪肠球菌和白色念珠菌的抑菌效果。以井周明显抑制带直径评价其抑菌活性。研究表明,Septillin与氢氧化钙联合使用和单独使用对链球菌、粪肠球菌和白色念珠菌都有相当大的抗菌活性,而芦荟与氢氧化钙结合使用对这三种细菌都有轻微的效果,但单独使用时效果不如Septillin和氢氧化钙。
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引用次数: 0
Correlation of Griva Parinaah (GP) in Anguli Praman and BMI in Medovriddhi (Obesity) w.s.r. to Cardiovascular Risk Anguli Praman的Griva Parinaah (GP)和medoriddhi(肥胖)w.s.r.的BMI与心血管风险的相关性
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.12
Kiran A. Tawalare, J. Pawar
The prevalence of overweight and obesity in India is increasing faster than the world average Medovriddhi (obesity) shows the symptoms as increased size of buttocks, breast and abdomen, Shwasa (breathlessness) after slight movement also. Acharya Bhavprakash added one more symptom the oversize of the neck (Griva). Acharya Sushruta mentioned the Griva measurement should be 20 Angul for both males and females with their fingers (self-finger unit). In modern science, body mass index (BMI) is used to find out obesity. Obesity is the foremost cause of cardiovascular diseases. BMI is the generalized metric way but Grivaparinaah in Swangulpramaan is a personalized quantifying anthropometric measurement. Individuals of Medovriddhi having an age group of 20 to 70 years were selected. So, intending to the height the importance of Grivaparinaah described in Medodhatu Vruddhi correlation study having been carried out. A positive correlation was found in GP with BMI in both genders having r-value of 0.3533 (p less than 0.05) for males and 0.3137 (p less than 0.05) for females. Using ROC curve analysis GP is >21.63 Angul for males and females were determined to be the best cut-off level for identifying a subject with BMI as cardiovascular risk.
印度超重和肥胖的流行率比世界平均水平增长得更快。肥胖的症状表现为臀部、乳房和腹部增大,轻微运动后也会出现呼吸困难。Acharya Bhavprakash又增加了一个症状:脖子过大。Acharya Sushruta提到,男性和女性的手指(自指单位)的格里瓦测量值都应该是20安格尔。在现代科学中,身体质量指数(BMI)被用来发现肥胖。肥胖是心血管疾病的首要原因。BMI是广义度量方法,而Swangulpramaan中的Grivaparinaah是一种个性化的量化人体测量方法。选取了年龄在20至70岁之间的梅多弗里迪个体。因此,为了高度强调《毗罗多陀》中所描述的毗罗多陀的重要性,开展了相关研究。男性GP与BMI均呈正相关,r值分别为0.3533 (p < 0.05)和0.3137 (p < 0.05)。通过ROC曲线分析,确定男性和女性的GP为bb0 21.63安圭尔为识别BMI为心血管危险的受试者的最佳截止水平。
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引用次数: 0
An experimental study to evaluate the antidotal activity of Neeli Moola (Indigofera tinctoria) Kalka w.s.r to haematological parameters in Vatsanabha (Aconitum ferox ) induced toxicity 研究了木楝对乌头中毒血液学指标的解毒作用
Pub Date : 2020-12-25 DOI: 10.21760/jaims.5.6.13
Sreelakshmi A, S. R., Sudhakara Bhat, S. K, C. Hebbar
Background: Vatsanabha is a potent cardiac poison comes under the category of Mahavisha with its main active principles aconitine, picraconine and pseudaconine. In the literatures there are descriptions about toxicants and in some traditional Malayalam textbooks antidotes has been explained under the concept “Prathyoushadha”. Neeli Moola has been mentioned as a Prathyoushadha for Vatsanabha poisoning in a renowned textbook „Visha Vaidya Jyotsnika‟. Hence to evaluate the antidotal activity in Vatsanabha poisoning, Neeli Moola Kalka has been used and the haematological parameters were analyzed to screen the results. Methods: Wistar strain albino rats were used in this study which were divided into 3 groups, normal control, toxic control and the test drug group. The duration of the study was 28 days .The data generated was mentioned as Mean±SEM. Difference among the groups was assessed by employing one way ANOVA followed by Dunnet‟s mul tiple „t‟ test. Results: Reversible action has been observed after the administration of Neeli Moola Kalka in the hematological parameters which has shown toxicity changes due to administration of Vatsanabha. Conclusion: Neeli Moola Kalka is having mild to moderate antidote effect in Vatsanbha induced toxicity.
背景:大毒是一种强效的心脏毒药,属于大毒的范畴,其主要活性成分是乌头碱、苦毒碱和假乌头碱。在文献中有关于毒物的描述,在一些传统的马拉雅拉姆教科书中,解毒剂被解释为“Prathyoushadha”的概念。Neeli Moola在著名的教科书《Visha Vaidya Jyotsnika》中被提及为Vatsanabha中毒的Prathyoushadha。因此,为了评价其对Vatsanabha中毒的解毒作用,我们采用了Neeli Moola Kalka,并对血液学参数进行了分析筛选。方法:以Wistar系白化大鼠为研究对象,将其分为正常对照组、中毒对照组和给药组。研究持续时间为28天,所得数据以Mean±SEM表示。采用单因素方差分析和Dunnet多重“t”检验来评估组间差异。结果:在给药后观察到可逆性作用,在血液学参数显示毒性变化,由于给药Vatsanabha。结论:枇杷膏有轻、中度解毒作用。
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引用次数: 0
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Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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