Effectiveness of Ex vivo Ultrasound for Detecting Sentinel Node Metastasis in Breast Cancer

E. Ahn, Hyun-Ah Kim, B. Moon, H. Choi, S. Sung
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Abstract

33 false positive false negative ex were 83.3%, 91.8%, 60.6%, 97.3%, 8.2%, 16.7% and 90.7% Conclusion: Ex vivo ultrasound evaluation for detecting sentinel lymph node during the be helpful to decide the extent lymph Purpose: The presence of lymph node metastasis is a key factor for deciding upon radical axillary dissection during a breast cancer operation. We performed prospective research to assess the accuracy and effectiveness of ex vivo ultrasound for detecting sentinel node metastasis during the operation. Methods: 183 fresh sentinel lymph nodes from 30 breast cancer patients had sonographic examination performed on them by a specialized radiologist immediately after surgical resection. The sonographic criteria for malignant lymph nodes were uneven cortical thickness, a node more than 3 mm in diameter, the absence of the hilum and a round hypoechoic node. After sonographic evaluation, the speci-men were delivered to the department of pathology for frozen biopsy and permanent staining. Results: Among 133 lymph nodes that were examined on frozen sectioning, 12 (9.0%) were revealed as metastatic nodes and 121 (90.9%) were revealed as benign. On US examination, 150 (81.9%) among the detected 183 nodes were read as benign and 33 (18.1%) were read as metastatic. Among 150 benign nodes, four (2.6%) were proven as metastasis on permanent pathology, and 20 (60.6%)
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体外超声检测乳腺癌前哨淋巴结转移的有效性
结论:体外超声检查在乳腺癌手术中发现前哨淋巴结有助于判断淋巴结的程度目的:淋巴结转移是否存在是决定是否进行根治性腋窝清扫的关键因素。我们进行了前瞻性研究,以评估手术中体外超声检测前哨淋巴结转移的准确性和有效性。方法:30例乳腺癌患者的183个新鲜前哨淋巴结在手术切除后立即由专业放射科医师对其进行超声检查。恶性淋巴结的超声诊断标准为皮质厚度不均、淋巴结直径大于3mm、淋巴结门缺失、圆形低回声淋巴结。超声评估后,标本被送到病理科进行冷冻活检和永久染色。结果:133例冷冻切片淋巴结中12例(9.0%)为转移性淋巴结,121例(90.9%)为良性淋巴结。在US检查中,发现的183个淋巴结中150个(81.9%)为良性,33个(18.1%)为转移性。150例良性淋巴结中,4例(2.6%)为永久性转移,20例(60.6%)为永久性转移。
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