Recent Advancements in Transdermal Drug Delivery System

M. Jahangir, Abdul Muheem, Chettupalli Anand, S. Imam
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引用次数: 7

Abstract

Transdermal drug delivery is one of the most promising methods for drug application. The administration of drugs by transdermal route offers the advantage of being relatively painless. Drug delivery with Transdermal patch systems exhibit slow, controlled drug release and absorption. Controlled drug delivery can be achieved by transdermal drug delivery system which can deliver the drug through skin to the systemic circulation at a predetermine rate over a prolonged period of time. Skin penetration enhancement technique have been developed to improve the bioavailability and increase the range of drug for which the transdermal and topical route is viable option. Characterization of transdermal patch is use to check it’s quality, size, time of onset & duration, adhesive property, thickness, weight of patch, moisture of content, uniformity & cutaneous toxicological studies. The market for transdermal products has been in a significant upward trend that is likely to continue for the foreseeable future.
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经皮给药系统研究进展
经皮给药是最有前途的药物应用方法之一。经皮给药具有相对无痛的优点。通过透皮贴片系统给药表现出缓慢、受控的药物释放和吸收。可通过透皮给药系统来实现受控的给药,该给药系统可以在长时间内以预定的速率将药物通过皮肤递送到体循环。皮肤渗透增强技术的发展是为了提高药物的生物利用度和增加药物的范围,透皮和局部途径是可行的选择。透皮贴片的特性是用来检查它的质量、大小、起效时间和持续时间、粘接性能、厚度、贴片重量、含水量、均匀性和皮肤毒理学研究。透皮产品的市场一直处于显著的上升趋势,在可预见的未来可能会持续下去。
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