Guiya Deng, Ke Huang, Xianchao Jiang, Kun Wang, Zihao Song, Yuchen Su, Chengming Li, Shuai Zhang, Shiqi Wang, Yaqin Huang
{"title":"Developments for collagen hydrolysates as a multifunctional antioxidant in biomedical domains","authors":"Guiya Deng, Ke Huang, Xianchao Jiang, Kun Wang, Zihao Song, Yuchen Su, Chengming Li, Shuai Zhang, Shiqi Wang, Yaqin Huang","doi":"10.1186/s42825-023-00131-9","DOIUrl":null,"url":null,"abstract":"<div><p>Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future.</p><h3>Graphical abstract</h3>\n <div><figure><div><div><picture><source><img></source></picture></div></div></figure></div>\n </div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-023-00131-9","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Leather Science and Engineering","FirstCategoryId":"1087","ListUrlMain":"https://link.springer.com/article/10.1186/s42825-023-00131-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Antioxidant collagen hydrolysates refers to the peptides mixture with antioxidant properties identified from hydrolyzed collagen. Due to its specific structural, biological and physicochemical properties, collagen hydrolysates have been explored as a multifunctional antioxidant in the biomedical field. In this review, we summarize recent advances in antioxidant collagen hydrolysates development. Initially, the preparation process of antioxidant collagen hydrolysates is introduced, including the production and separation methods. Then the effects and the mechanisms of amino acid composition and collagen peptide structure on the antioxidant activity of collagen hydrolysates are reviewed. Finally, the applications of antioxidant collagen hydrolysates in biomedical domains are summarized, with critical discussions about the advantages, current limitations and challenges to be resolved in the future.