Sergio Charles-Lozoya , Gibran Ruíz-Zenteno , María E. Lizcano-Martínez , Héctor Cobos-Aguilar , Joél León-Ruíz , Jesús Domínguez-Delgado
{"title":"Vertebral coccidioidomycosis with mechanical instability treated solely with antifungals: A case report","authors":"Sergio Charles-Lozoya , Gibran Ruíz-Zenteno , María E. Lizcano-Martínez , Héctor Cobos-Aguilar , Joél León-Ruíz , Jesús Domínguez-Delgado","doi":"10.1016/j.mmcr.2023.100615","DOIUrl":null,"url":null,"abstract":"<div><p>Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"42 ","pages":"Article 100615"},"PeriodicalIF":1.6000,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753923000477/pdfft?md5=3d11cc44d084849d4f7e592184ac3fb1&pid=1-s2.0-S2211753923000477-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753923000477","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.