Pub Date : 2024-11-23DOI: 10.1016/j.mmcr.2024.100685
Andrzej Kazimierz Jaworek , Przemysław Hałubiec , Paweł Marcin Krzyściak , Anna Wojas-Pelc , Jadwiga Wójkowska-Mach , Jacek Cezary Szepietowski
We report a case of a 75-year-old male with suspected onychomycosis of the right hand and both feet who also developed kerion-like changes in the skin of his head and neck after recent inguinal hernia surgery. A mycological examination revealed the presence of Trichophyton rubrum in all affected sites. Treatment with oral terbinafine and topical isoconazole nitrate was started, resulting in a significant improvement in skin lesions. The case we present underscores the possibility of autoinoculation transmission of dermatophytes and the need for a careful evaluation of the coexistence of mycoses at different anatomical sites.
{"title":"Kerion-like lesions following an autoinoculation event in patient with chronic onychomycosis – Case report","authors":"Andrzej Kazimierz Jaworek , Przemysław Hałubiec , Paweł Marcin Krzyściak , Anna Wojas-Pelc , Jadwiga Wójkowska-Mach , Jacek Cezary Szepietowski","doi":"10.1016/j.mmcr.2024.100685","DOIUrl":"10.1016/j.mmcr.2024.100685","url":null,"abstract":"<div><div>We report a case of a 75-year-old male with suspected onychomycosis of the right hand and both feet who also developed kerion-like changes in the skin of his head and neck after recent inguinal hernia surgery. A mycological examination revealed the presence of <em>Trichophyton rubrum</em> in all affected sites. Treatment with oral terbinafine and topical isoconazole nitrate was started, resulting in a significant improvement in skin lesions. The case we present underscores the possibility of autoinoculation transmission of dermatophytes and the need for a careful evaluation of the coexistence of mycoses at different anatomical sites.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100685"},"PeriodicalIF":1.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-16DOI: 10.1016/j.mmcr.2024.100683
Terenzio Cosio , Ruslana Gaeta Shumak , Cristiana Borselli , Fabio Artosi , Roberta Gaziano , Elena Campione
Psoriasis is a multifactorial immune-mediated disorder linked to the interleukin (IL)-17 signalling pathway. We present an unusual case of tinea corporis and faciei caused by Trichophyton tonsurans that developed after starting the IL-17A/F inhibitor bimekizumab. Our case underlines how psoriatic patients, treated with IL-17 inhibitors, should be screened for cutaneous fungal infections before and during treatment, in order to exclude a concomitant infection or the risk of its exacerbation.
{"title":"Challenging case of tinea corporis and faciei in psoriatic patient treated with bimekizumab: The usefulness of mycological screening before biological therapies","authors":"Terenzio Cosio , Ruslana Gaeta Shumak , Cristiana Borselli , Fabio Artosi , Roberta Gaziano , Elena Campione","doi":"10.1016/j.mmcr.2024.100683","DOIUrl":"10.1016/j.mmcr.2024.100683","url":null,"abstract":"<div><div>Psoriasis is a multifactorial immune-mediated disorder linked to the interleukin (IL)-17 signalling pathway. We present an unusual case of <em>tinea corporis</em> and <em>faciei</em> caused by <em>Trichophyton tonsurans</em> that developed after starting the IL-17A/F inhibitor bimekizumab. Our case underlines how psoriatic patients, treated with IL-17 inhibitors, should be screened for cutaneous fungal infections before and during treatment, in order to exclude a concomitant infection or the risk of its exacerbation.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100683"},"PeriodicalIF":1.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report a case of onychomycosis due to Fusarium solani with gray-green staining, which improved after nail plate removal and antifungal liquid of effinaconazole. Fungal cultures revealed light-brown and dark-green colonies. Gray-green nail might have occurred due to the combination of these colonies, which necessitated differentiation from green nail. Fusarium solani was detected on the genetic analysis of the colonies. Fusarium species reportedly produce yellow or red pigments; however, Fusarium species has not been previously reported to produce green pigments or forming dark-green colonies in fungal cultures.
{"title":"Onychomycosis with gray-green staining caused by Fusarium solani","authors":"Yoshihito Mima , Masako Yamamoto , Koichi Makimura , Ken Iozumi","doi":"10.1016/j.mmcr.2024.100684","DOIUrl":"10.1016/j.mmcr.2024.100684","url":null,"abstract":"<div><div>We report a case of onychomycosis due to Fusarium solani with gray-green staining, which improved after nail plate removal and antifungal liquid of effinaconazole. Fungal cultures revealed light-brown and dark-green colonies. Gray-green nail might have occurred due to the combination of these colonies, which necessitated differentiation from green nail. Fusarium solani was detected on the genetic analysis of the colonies. Fusarium species reportedly produce yellow or red pigments; however, Fusarium species has not been previously reported to produce green pigments or forming dark-green colonies in fungal cultures.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100684"},"PeriodicalIF":1.6,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-31DOI: 10.1016/j.mmcr.2024.100682
Estelle Sabourin , Clémentine De La Porte des Vaux , Nathanaël Veluppillai , Marie-Elisabeth Bougnoux , Eric Dannaoui , Olivier Lortholary
Candida blankii is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical C. blankii metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease. The patient was initially treated by a combination of voriconazole and 5-fluorocytosine (5-FC). However, the treatment was subsequently changed to posaconazole and then to a combination of caspofungin and 5-FC.
2012 Elsevier Ltd. All rights reserved.
空白念珠菌是最近报道的一种导致罕见真菌病的酵母菌。该菌种对氟康唑和棘白菌素的最低抑菌浓度（MIC）很高。我们报告了一名慢性肉芽肿病患者的非典型 C. blankii 掌指关节骨关节感染病例。患者最初接受了伏立康唑和 5-氟胞嘧啶（5-FC）的联合治疗。然而，治疗随后改为泊沙康唑，然后又改为卡泊芬净和5-FC联合疗法。2012 Elsevier Ltd. 版权所有。
{"title":"Case report: Candida blankii osteo-articular infection in a patient with Chronic Granulomatous Disease","authors":"Estelle Sabourin , Clémentine De La Porte des Vaux , Nathanaël Veluppillai , Marie-Elisabeth Bougnoux , Eric Dannaoui , Olivier Lortholary","doi":"10.1016/j.mmcr.2024.100682","DOIUrl":"10.1016/j.mmcr.2024.100682","url":null,"abstract":"<div><div><em>Candida blankii</em> is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical <em>C. blankii</em> metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease. The patient was initially treated by a combination of voriconazole and 5-fluorocytosine (5-FC). However, the treatment was subsequently changed to posaconazole and then to a combination of caspofungin and 5-FC.</div><div>2012 Elsevier Ltd. All rights reserved.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100682"},"PeriodicalIF":1.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-26DOI: 10.1016/j.mmcr.2024.100680
Kristoffer E. Leon , Timothy Mugabi , Tu Tran , Hawa Magembe , Caleb P. Skipper
Cryptococcal meningitis is a fungal infection that is typically caused by Cryptococcus neoformans and most commonly seen in severely immunosuppressed patient. This disease causes severe neurologic disease due to elevated intracranial pressures. In this case report, we describe a patient with newly diagnosed HIV presenting to the hospital with cryptococcal meningitis complicated by sudden vision loss. We highlight the role of prompt diagnosis and treatment in the reversal of vision loss, with subsequent monitoring using a handheld, non-mydriatic fundus imaging device.
{"title":"Utility of handheld non-mydriatic fundoscopy in a case of bilateral, reversible vision loss in an advanced HIV patient with cryptococcal meningitis in Sub-Saharan Africa","authors":"Kristoffer E. Leon , Timothy Mugabi , Tu Tran , Hawa Magembe , Caleb P. Skipper","doi":"10.1016/j.mmcr.2024.100680","DOIUrl":"10.1016/j.mmcr.2024.100680","url":null,"abstract":"<div><div>Cryptococcal meningitis is a fungal infection that is typically caused by <em>Cryptococcus neoformans</em> and most commonly seen in severely immunosuppressed patient. This disease causes severe neurologic disease due to elevated intracranial pressures. In this case report, we describe a patient with newly diagnosed HIV presenting to the hospital with cryptococcal meningitis complicated by sudden vision loss. We highlight the role of prompt diagnosis and treatment in the reversal of vision loss, with subsequent monitoring using a handheld, non-mydriatic fundus imaging device.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100680"},"PeriodicalIF":1.6,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142654257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-26DOI: 10.1016/j.mmcr.2024.100681
Agustin N. Posso, Alvaro A. Perez-Meza, Paul Marquez, Daniel Garzon-Chavez
Introduction
Cutaneotrichosporon debeurmannianum is a yeast-like anamorphic rare fungus commonly found in tropical areas. This case report is the first one located in South America.
Case report
A 67-year-old patient presented with a 5-year history of right foot pain attributed to foot trauma while at sea 5 years prior. During surgical exploration, an impressive whitish cerebriform-like cyst was encountered. Genetic analysis using the genes ITS1, ITS4, LSU-R, and LSU-F was performed, and a phylogenetic tree identified C. debeurmannianum.
Conclusion
A complete characterization of this fungus which causes human disease has not yet been achieved and more research is needed.
{"title":"A unique presentation of subcutaneous Cutaneotrichosporon debeurmannianum infection: A case report of a diagnostic challenge","authors":"Agustin N. Posso, Alvaro A. Perez-Meza, Paul Marquez, Daniel Garzon-Chavez","doi":"10.1016/j.mmcr.2024.100681","DOIUrl":"10.1016/j.mmcr.2024.100681","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Cutaneotrichosporon debeurmannianum</em> is a yeast-like anamorphic rare fungus commonly found in tropical areas. This case report is the first one located in South America.</div></div><div><h3>Case report</h3><div>A 67-year-old patient presented with a 5-year history of right foot pain attributed to foot trauma while at sea 5 years prior. During surgical exploration, an impressive whitish cerebriform-like cyst was encountered. Genetic analysis using the genes ITS1, ITS4, LSU-R, and LSU-F was performed, and a phylogenetic tree identified <em>C. debeurmannianum</em>.</div></div><div><h3>Conclusion</h3><div>A complete characterization of this fungus which causes human disease has not yet been achieved and more research is needed.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100681"},"PeriodicalIF":1.6,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142529496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fungal infections in marine animals, particularly pinnipeds, have seen a notable increase, often linked to compromised immune systems in captive environments. Trichophyton species, while common in terrestrial mammals, have sporadically caused dermatophytosis in pinnipeds. A South American sea lion (Otaria byronia) presented with Trichophyton benhamiae infection, marking the first such case in this species. Effective treatment combined oral terbinafine with topical ozonized oil, supported by silymarin for liver protection. Accurate fungal identification and sensitivity testing were key to the successful management and recovery of the patient.
{"title":"Dermatophytosis caused by Trichophyton benhamiae in a sea lion. First report","authors":"Ronar López , Víctor Silva , Viviana Bown , Patricio Godoy-Martínez , Pamela Thomson","doi":"10.1016/j.mmcr.2024.100679","DOIUrl":"10.1016/j.mmcr.2024.100679","url":null,"abstract":"<div><div>Fungal infections in marine animals, particularly pinnipeds, have seen a notable increase, often linked to compromised immune systems in captive environments. <em>Trichophyton</em> species, while common in terrestrial mammals, have sporadically caused dermatophytosis in pinnipeds. A South American sea lion (<em>Otaria byronia</em>) presented with <em>Trichophyton benhamiae</em> infection, marking the first such case in this species. Effective treatment combined oral terbinafine with topical ozonized oil, supported by silymarin for liver protection. Accurate fungal identification and sensitivity testing were key to the successful management and recovery of the patient.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100679"},"PeriodicalIF":1.6,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18DOI: 10.1016/j.mmcr.2024.100676
Kaixuan Yuan , Xiaoxiao Wang , Yong Ling, Ye Long, Zhuoxi Chen, Yunhu Zhao
Fungal peritonitis, an uncommon complication in continuous ambulatory peritoneal dialysis (CAPD), has recently garnered increased attention due to its incidence and potential mortality. To the best of our knowledge, this is the first confirmed case of Neosartorya hiratsukae (N. hiratsukae) causing CAPD-related peritonitis in a patient with chronic nephrotic syndrome in Guangzhou, China. After prompt removal of the peritoneal catheter and active antifungal therapy, no clinical manifestations of peritonitis were observed. Our report underscores the importance of enhancing clinical awareness regarding N. hiratsukae and ensuring timely diagnosis in cases of CAPD-related fungal peritonitis.
{"title":"First case of fungal peritonitis caused by Neosartorya hiratsukae in China","authors":"Kaixuan Yuan , Xiaoxiao Wang , Yong Ling, Ye Long, Zhuoxi Chen, Yunhu Zhao","doi":"10.1016/j.mmcr.2024.100676","DOIUrl":"10.1016/j.mmcr.2024.100676","url":null,"abstract":"<div><div>Fungal peritonitis, an uncommon complication in continuous ambulatory peritoneal dialysis (CAPD), has recently garnered increased attention due to its incidence and potential mortality. To the best of our knowledge, this is the first confirmed case of <em>Neosartorya hiratsukae</em> (<em>N. hiratsukae</em>) causing CAPD-related peritonitis in a patient with chronic nephrotic syndrome in Guangzhou, China. After prompt removal of the peritoneal catheter and active antifungal therapy, no clinical manifestations of peritonitis were observed. Our report underscores the importance of enhancing clinical awareness regarding <em>N. hiratsukae</em> and ensuring timely diagnosis in cases of CAPD-related fungal peritonitis.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100676"},"PeriodicalIF":1.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15DOI: 10.1016/j.mmcr.2024.100677
Siyue Kan , Lulu Li , Lulu An , Hong Yang , Lianjuan Yang
An 82-year-old female patient presented to our clinic with refractory nailbed ulceration accompanied by pain in her left fourth toe. Six months prior, she had undergone nail removal surgery to address a persistent paronychia that had not resolved for four months. Crust, necrotic tissue, and secretion on the nailbed were taken for microbiological examination, and Candida parapsilosis was discovered in culture. The authors first report one refractory nailbed ulceration caused by Candida parapsilosis after nail extraction.
{"title":"The refractory nailbed ulceration caused by Candida parapsilosis after nail extraction","authors":"Siyue Kan , Lulu Li , Lulu An , Hong Yang , Lianjuan Yang","doi":"10.1016/j.mmcr.2024.100677","DOIUrl":"10.1016/j.mmcr.2024.100677","url":null,"abstract":"<div><div>An 82-year-old female patient presented to our clinic with refractory nailbed ulceration accompanied by pain in her left fourth toe. Six months prior, she had undergone nail removal surgery to address a persistent paronychia that had not resolved for four months. Crust, necrotic tissue, and secretion on the nailbed were taken for microbiological examination, and <em>Candida parapsilosis</em> was discovered in culture. The authors first report one refractory nailbed ulceration caused by <em>Candida parapsilosis</em> after nail extraction.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100677"},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142529694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15DOI: 10.1016/j.mmcr.2024.100678
Muhammad Absar , Ahmed Alduwayrij , Abdulmajeed Al-Arfaj , Zafar Shah , Fahad Nashmy , Mohamed Tahar Yacoubi
Candida meningitis is almost always caused by Candia albicans, but other species, such as Candida dubliniensis, can cause it on rare occasions. C. dubliniensis is increasingly linked to immunocompromised hosts but also affects immunocompetent hosts. To the best of our knowledge, we present the ninth (9th) case of C. dubliniensis meningitis, the first from Saudi Arabia. A 70-year-old woman with multiple comorbidities presented with confusion, poor oral intake, and left upper limb swelling for two weeks. C. dubliniensis was isolated and treated with liposomal amphotericin and anidulafungin. The scarcity of such infections makes the best treatment regimen undetermined.
{"title":"Meningitis caused by Candida dubliniensis in a patient with liver cirrhosis: A case report and review of the literature","authors":"Muhammad Absar , Ahmed Alduwayrij , Abdulmajeed Al-Arfaj , Zafar Shah , Fahad Nashmy , Mohamed Tahar Yacoubi","doi":"10.1016/j.mmcr.2024.100678","DOIUrl":"10.1016/j.mmcr.2024.100678","url":null,"abstract":"<div><div>Candida meningitis is almost always caused by <em>Candia albicans</em>, but other species, such as <em>Candida dubliniensis</em>, can cause it on rare occasions. <em>C. dubliniensis</em> is increasingly linked to immunocompromised hosts but also affects immunocompetent hosts. To the best of our knowledge, we present the ninth (9th) case of <em>C. dubliniensis</em> meningitis, the first from Saudi Arabia. A 70-year-old woman with multiple comorbidities presented with confusion, poor oral intake, and left upper limb swelling for two weeks. <em>C. dubliniensis</em> was isolated and treated with liposomal amphotericin and anidulafungin. The scarcity of such infections makes the best treatment regimen undetermined.</div></div><div><h3>2012 Elsevier Ltd</h3><div>All rights reserved.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"46 ","pages":"Article 100678"},"PeriodicalIF":1.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号