{"title":"Protein nanocage engineering for Pickering emulsions and potential food applications","authors":"Samuel Watts, Chase Jia Jing Chow, Sierin Lim","doi":"10.1016/j.cocis.2023.101761","DOIUrl":null,"url":null,"abstract":"<div><p><span>Protein nanocages used as emulsion stabilizing colloidal particles are opening possibilities to the design of novel delivery systems for food, pharmaceutical and cosmetic applications. Protein nanocage-stabilized emulsions are able to co-deliver hydrophilic and hydrophobic compounds. The surface chemistry of the particles is one of the factors that determines their ability to stabilize the emulsion. Hence, the importance in developing strategies to rationally tailor the nanocage surface chemistry. This contribution summarizes recent advances in protein nanocage </span>Pickering emulsions and the methods used to modify the nanocages. It discusses future strategies that may allow the modification of protein nanocages based on current knowledge of Pickering emulsions and protein nanocage engineering technology. The characterization methods for the investigation of these protein nanocages and nanocage stabilized emulsions are described. Finally, the applications of protein nanocages for nutrient delivery in the gastrointestinal tract will be discussed. This contribution provides a perspective for future work on protein nanocage stabilized emulsions.</p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":null,"pages":null},"PeriodicalIF":7.9000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Colloid & Interface Science","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1359029423000869","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Protein nanocages used as emulsion stabilizing colloidal particles are opening possibilities to the design of novel delivery systems for food, pharmaceutical and cosmetic applications. Protein nanocage-stabilized emulsions are able to co-deliver hydrophilic and hydrophobic compounds. The surface chemistry of the particles is one of the factors that determines their ability to stabilize the emulsion. Hence, the importance in developing strategies to rationally tailor the nanocage surface chemistry. This contribution summarizes recent advances in protein nanocage Pickering emulsions and the methods used to modify the nanocages. It discusses future strategies that may allow the modification of protein nanocages based on current knowledge of Pickering emulsions and protein nanocage engineering technology. The characterization methods for the investigation of these protein nanocages and nanocage stabilized emulsions are described. Finally, the applications of protein nanocages for nutrient delivery in the gastrointestinal tract will be discussed. This contribution provides a perspective for future work on protein nanocage stabilized emulsions.
期刊介绍:
Current Opinion in Colloid and Interface Science (COCIS) is an international journal that focuses on the molecular and nanoscopic aspects of colloidal systems and interfaces in various scientific and technological fields. These include materials science, biologically-relevant systems, energy and environmental technologies, and industrial applications.
Unlike primary journals, COCIS primarily serves as a guide for researchers, helping them navigate through the vast landscape of recently published literature. It critically analyzes the state of the art, identifies bottlenecks and unsolved issues, and proposes future developments.
Moreover, COCIS emphasizes certain areas and papers that are considered particularly interesting and significant by the Editors and Section Editors. Its goal is to provide valuable insights and updates to the research community in these specialized areas.