Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review

Q4 Medicine Oftalmologiya Pub Date : 2023-09-30 DOI:10.18008/1816-5095-2023-3-398-404
A. N. Kulikov, M. V. Zakharov, A. A. Volozhev
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Abstract

Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of that pathology. The causes of age-related macular degeneration are not fully understood, in spite of keeping a great amount of knowledge at etiology, pathogenesis, diagnosis and modern types of treatment. The problem of age-related macular degeneration treatment has remained actual nowadays. Now, the medicine doesn’t have etiotropic treatment of AMD, because we still don’t know a definite etiologic factor of this developing disease. The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. The disadvantage of current treatment methods is a narrow focus at one of the pathogenesis components or using as symptomatic therapy. The analysis of literature date has allowed noticing of using of an extracorporeal hemocorrection as perspective way at exploration of new methods of treatment of dry age-related macular degeneration.
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干型老年性黄斑变性的治疗方法-历史与展望。审查
年龄相关性黄斑变性是导致视力丧失的主要原因,也是全世界成年人日益严重的残疾问题。该报告涵盖了该病理的历史要点、危险因素、发病机制、分类和目前的治疗方法。尽管对老年性黄斑变性的病因、发病机制、诊断和现代治疗方法有大量的了解,但其病因尚不完全清楚。老年性黄斑变性的治疗问题至今仍然存在。现在,药物并没有对黄斑变性的病因治疗,因为我们仍然不知道这种疾病发展的确切病因。湿性AMD的主要治疗方法是注射抗vegf药物。目前,干性老年性黄斑变性的治疗包括改变危险因素(戒烟、健康的生活方式等)和含有某些成分(维生素C、维生素E、锌、铜和叶黄素与玉米黄质或β -胡萝卜素)的膳食补充剂的组合,可能能够减缓疾病的进展。目前治疗方法的缺点是局限于某一致病成分或作为对症治疗。对文献资料的分析已经允许注意到使用体外血液矫正作为探索治疗干性年龄相关性黄斑变性的新方法的透视方式。
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来源期刊
Oftalmologiya
Oftalmologiya Medicine-Ophthalmology
CiteScore
0.60
自引率
0.00%
发文量
93
审稿时长
8 weeks
期刊介绍: The scientific journal Oftalmologiya is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Ophthalmology, Физиология, Клиническая медицина, Профилактическая медицина, Медико-биологические науки, Фармацевтические науки. Before sending a scientific article, we recommend you to read the section For authors. This will allow you to prepare an article better for publication, to make it more interesting for the readers and useful for the scientific community. By following these steps, you will greatly increase the likelihood of your scientific article publishing in journals included in international citation systems (e.g., Scopus). Then you may choose a different journal, select the journal included to list of SAC Russia journal list, or send your scientific work for review and publication.
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