Comparison of 12, 14 And 16 Core Prostate Biopsies in Detecting Prostate Cancer in Patients: A Comparative Study

Abstract

Prostate cancer is one of the most common cancers in men and early detection is vital for effective treatment. The traditional method for diagnosis includes the use of prostate biopsies, where a needle is used to extract tissue samples from the prostate gland to be analyzed for cancerous cells. Objective: To evaluate and compare the diagnosis rates of benign, malign, and intermediate conditions in patients subjected to 12-core, 14-core, and 16-core biopsy techniques. Methods: The retrospective study was conducted on patients who visited our clinic and underwent prostate biopsy between the years 2013 and 2021. This study revolved around a careful comparative examination of the diagnostic outcomes from three different prostate biopsy techniques – 12-core, 14-core, and 16-core biopsy. Reults: The findings indicated that there were no notable variations in age or PSA levels among the groups. The 12-core group showed 44.8% benign, 17.8% malign, and 37.4% borderline cases. The 14-core group revealed 43.1% benign, 31.4% malign, and 25.5% borderline cases. The 16-core group had 32% benign, 42.7% malign, and 25.2% borderline cases (p<0.001). Conclusions: The 16-core biopsy yielded the highest malignancy detection.