The Effect of Chitosan and Polyvinyl Alcohol Combination on Physical Characteristics and Mechanical Properties of Chitosan-PVA-Aloe vera Film

Dioni fadia Zatalini, Esti Hendradi, None Philip Drake, Retno Sari
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Abstract

Background: Wound is a condition where there is damage or disruption to the anatomical structure and function of the skin. Wounds that are not treated properly can lead to infection. As wound dressings, film dressings have many advantages such as being elastic, flexible, transparent, and can adapt to the wound shape. Film’s characteristics of are affected by the plasticizer and the polymer. Combination of chitosan and polyvinyl alcohol (PVA) is able to improve the mechanical properties of the film such as its swelling capacity, tensile strength, and elongation at break. Objective: This study aims to determine the effects of chitosan and PVA in various concentrations on the physical characteristics and mechanical properties of the film. Methods: Film was prepared by solvent casting method, using chitosan and alginate in various concentrations of 0% to 1.5%, 1.5% Aloe vera, and 6% propylene glycol. Films’ characteristics and mechanical properties were evaluated, such as swelling index, tensile strength, elongation at break, and Young’s modulus. Results: The result showed that chitosan and PVA polymers had a significant effect on the swelling index, tensile strength, elongation at break, and Young’s modulus. The effect of chitosan and PVA combination on the swelling index, tensile strength, and elongation at break is due to the hydrogen bonding between the hydroxyl group of PVA and the amine group of chitosan. Conclusion: The combination of chitosan and polyvinyl alcohol influenced the film's physical and mechanical properties. Film with chitosan and polyvinyl alcohol ratio of 1.5%:1.5% have best characteristics compared to others.
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壳聚糖和聚乙烯醇复合对壳聚糖-聚乙烯醇-芦荟膜物理特性和力学性能的影响
背景:伤口是皮肤解剖结构和功能受到损伤或破坏的一种情况。伤口处理不当会导致感染。膜敷料作为伤口敷料,具有弹性好、柔韧性好、透明、能适应伤口形态等优点。增塑剂和聚合物对薄膜的性能有影响。壳聚糖和聚乙烯醇(PVA)的结合可以改善薄膜的力学性能,如膨胀能力、抗拉强度和断裂伸长率。目的:研究不同浓度的壳聚糖和聚乙烯醇对薄膜物理特性和力学性能的影响。方法:以0% ~ 1.5%浓度的壳聚糖和海藻酸盐、1.5%芦荟、6%丙二醇为原料,采用溶剂铸造法制备膜。对薄膜的特性和力学性能进行了评价,如膨胀指数、拉伸强度、断裂伸长率和杨氏模量。结果:壳聚糖和聚乙烯醇聚合物对膨胀指数、抗拉强度、断裂伸长率和杨氏模量均有显著影响。壳聚糖与PVA复合对膨胀指数、抗拉强度和断裂伸长率的影响是由于PVA的羟基与壳聚糖的胺基之间的氢键作用。结论:壳聚糖与聚乙烯醇复合对膜的物理力学性能有影响。壳聚糖与聚乙烯醇配比为1.5%时,薄膜性能最佳。
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发文量
26
审稿时长
12 weeks
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