Treatment Options for Patients with Inflammatory Bowel Disease During the COVID-19 Epidemic: A Review

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Abstract

The Corona Virus Disease (COVID-19) outbreak is affecting life around the world. In particular, people with basic diseases are concerned about whether COVID-19 will affect their original disease,Increasing attention is whether patients with inflammatory bowel disease (IBD) are more susceptible to COVID-19.Whether the treatment plans need to be adjusted, Summary literature shows that IBD patients have comparable infection rates as those in the general population, patients with IBD using biologics are more likely to develop asymptomatic infections and have fewer symptoms than normal populations, The use of parenteral-selective biologic agents may have a protective effect in lung function, which may be associated with its mitigation of cytokine storm syndrome. So patients with IBD should not interrupt the original biological treatment regimen. However, in preparation selection, parenteral-selective biological agents are preferred.
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COVID-19流行期间炎症性肠病患者的治疗方案:综述
冠状病毒病(COVID-19)的爆发正在影响世界各地的生活。特别是基础疾病患者关注的是新冠病毒是否会影响其原有疾病,炎症性肠病(IBD)患者是否更容易感染新冠病毒越来越受到关注。是否需要调整治疗方案,综述文献显示,IBD患者的感染率与普通人群相当,使用生物制剂的IBD患者更容易发生无症状感染,症状比正常人群少,使用肠外选择性生物制剂可能对肺功能有保护作用,这可能与其缓解细胞因子风暴综合征有关。因此,IBD患者不应中断原有的生物治疗方案。然而,在制剂选择上,首选非肠外选择性生物制剂。
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