Comparison of Graft Survival in Kidney Transplant Recipients Over 50 Years and Under 50 Years in Tabriz Imam Reza Hospital

Abstract

Introduction Chronic kidney failure is one of the most common diseases in the world. The prevalence and incidence of end-stage renal disease are increasing in developed and developing countries, bringing a tremendous financial burden to healthcare systems. Therefore, according to the above, this study aims to compare graft survival in kidney transplant recipients over 50 years old and under 50 years old in Imam Reza Hospital, Tabriz, Iran. Methods Following approval from the Regional Research Ethics Committee, a retrospective study was conducted on all patients admitted to Imam Reza Hospital in Tabriz in 2020 who underwent kidney transplantation. Results This study included 74 patients, of which 50 (67.6%) were male, and 24 (32.4%) were female. The mean age of the transplant recipients was 40.91 ± 14.20, with 47 (63.5%) being under 50 years of age and 27 (36.5%) aged 50 or above. Of these patients, 8 (10.8%) were deceased, and 66 (89.2%) were living cases. The left kidney was transplanted in 67 (90.5%) and the right kidney in 7 (9.5%). The mean age of the deceased patients (8 patients) was 53.37 ± 9.73, while the mean age of the living patients (66 patients) was 39.40 ± 13.96, resulting in a statistically significant difference (p < 0.01). Additionally, 6 (22.2%) of the patients aged 50 and above who underwent transplantation died, compared to 4.3% in the patients aged under 50 (2 patients); this was also statistically significant (p = 0.01). Conclusion The results of the study, which involved 74 patients, revealed that there was no significant difference in gender and side of the transplanted kidney between the two groups; however, age was found to be an important factor in patient survival.