A Review on Analytical Method Development and Validation for the Simultaneous Estimation of Rosuvastatin and Fimasartan in Bulk and its Pharmaceuticle Dosage Form

Suresh Kumar, Nirma Chavda
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Abstract

Hypertension is a popular disease that is specified by having a lot of quantity of pressure in blood vessels than normal. High blood pressure is a very general disorder, especially past middle age. It is a vital risk issue for cardiovascular mortality. For enhanced activity of hypertension, Rosuvastatin and Fimasartan are newer combination in the market, which is effective in High blood pressure. This combination was developed to enhance medication for Stage II Hypertension. This article gives information about totally different analytical method development like spectrophotometric and chromatographic methods reported for Rosuvastatin and Fimasartan for individual and other drug combinations. All reported methods were found to be simple, accurate, economic, precise and reproducible in nature. This Review delivers on latest development in analytical method development for Rosuvastatin and Fimasartan, and there are no methods reported for this combination as per our knowledge.
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瑞舒伐他汀和非马沙坦原料药及其剂型同时测定分析方法的开发与验证综述
高血压是一种常见的疾病,它的特点是血管中的压力比正常情况下要大。高血压是一种非常普遍的疾病,尤其是中年以后。这是心血管死亡的一个重要风险问题。瑞舒伐他汀和非马沙坦是市场上较新的联合用药,对高血压有较好的疗效。这种组合是为了加强II期高血压的药物治疗。本文介绍了瑞舒伐他汀和非马沙坦的不同分析方法的发展,如分光光度法和色谱法,用于单独和其他药物组合。所有方法简便、准确、经济、精密度高、重复性好。本综述提供了瑞舒伐他汀和非马沙坦分析方法开发的最新进展,据我们所知,尚无针对该组合的分析方法报道。
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