Evaluating the Regenerative Capacity of Novel Platelet Concentrate (PC)-Titanium Platelet Rich Fibrin (T-PRF) in the field of Dentistry. A Narrative Review.

Abstract

Periodontal disease treatment is always a challenging task. Various treatment modalities have been applied for treating this painless chronic condition. With advancement in the field of research in dentistry researchers shifted towards the autologous products hence came the usage of platelet concentrates in various branches of dentistry. Initially fibrin glue, platelet rich plasma (PRP) have been tried but because of their drawbacks platelet rich fibrin (PRF) came into play. Due to possible contamination of silica particles in silica tubes or silica coated plastic tubes and shorter resorption time, titanium attracted the researchers. This lead to introduction of titanium platelet rich fibrin (T-PRF) a second generation platelet concentrate. This had a thicker fibrin meshwork, better cellular entrapment, greater resorption rate and titanium tubes are inert, better haemocompatible and non-corrosive. It also eliminates the possible contamination of silica test tubes and silica coated plastic tubes. Present article is a review on T-PRF and its usage in the field of dentistry.