The effect of menopause on lipoprotein (a) concentrations: a systematic review and meta-analysis

Panagiotis Anagnostis, Christina Antza, Christina Trakatelli, Irene Lambrinoudaki, Dimitrios Goulis, Vasileios Kotsis
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Abstract

Objective: Transition to menopause has been associated with an increased risk of cardiovascular disease (CVD), attributed mainly to atherogenic dyslipidemia. Whether lipoprotein (a) [Lp(a)], an independent cardiovascular risk factor, also contributes to menopause-associated CVD has not yet been clarified. The aim of this study was to systematically investigate and meta-analyze the best available evidence regarding the effect of menopause on Lp(a) concentrations.
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绝经对脂蛋白(a)浓度的影响:一项系统回顾和荟萃分析
目的:过渡到更年期与心血管疾病(CVD)的风险增加有关,主要归因于动脉粥样硬化性血脂异常。是否脂蛋白(a) [Lp(a)],一个独立的心血管危险因素,也有助于更年期相关的心血管疾病尚未明确。本研究的目的是系统地调查和荟萃分析有关绝经对Lp(a)浓度影响的最佳现有证据。
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