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Does loneliness impair immunity? 孤独会损害免疫力吗?
Pub Date : 2024-08-23 DOI: 10.1016/j.maturitas.2024.108095
Amrit Kahlon, Steven Lippmann, Jack Feehan, Vasso Apostolopoulos, Ranjit Sah
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引用次数: 0
Equitable cervical cancer screening for women with disabilities. 为残疾妇女提供公平的宫颈癌筛查。
Pub Date : 2024-08-22 DOI: 10.1016/j.maturitas.2024.108094
Dan Wu, Eneyi E Kpokiri, Luthfi Azizatunnisa', Sara Rotenberg, Hannah Kuper, Joseph D Tucker
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引用次数: 0
"We're only as needy as our unmet needs". "只有我们的需求没有得到满足,我们才会有需要"。
Pub Date : 2024-08-01 Epub Date: 2024-05-11 DOI: 10.1016/j.maturitas.2024.108025
Dimitrios G Goulis
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引用次数: 0
Contextualising free-living gait with computer vision 利用计算机视觉将自由行走步态情景化
Pub Date : 2024-07-01 DOI: 10.1016/j.maturitas.2024.108065
Jason Moore, Alan Godfrey
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引用次数: 0
Management of ovarian cysts in postmenopausal women 绝经后妇女卵巢囊肿的处理
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.164
Salma Bouguerra, Syrine Ben Saidane, Badreddine Bouguerra
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引用次数: 0
Menopausal symptom burden and quality of life in women with breast cancer on endocrine adjuvant therapy: findings from the REALISE study 内分泌辅助治疗对乳腺癌妇女绝经期症状负担和生活质量的影响:来自realize研究的发现
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.163
Tommaso Simoncini, Nils Schoof, Siir Su Saydam, Cecilia Caetano, Cecile Janssenswillen, Megan Scott, Mia Harvey, Carsten Moeller, Katrin Schaudig, Victoria Banks
Background: Women receiving endocrine adjuvant (EA) therapy after breast cancer treatment report high rates of menopausal symptoms including vasomotor symptoms (VMS). VMS impact quality of life and can lead to treatment discontinuation and reduced survival, but existing literature evaluating symptom burden and impact is limited. The REAL-world evIdence on vasomotor and other Symptoms in menopausal womEn (REALISE) study aimed to evaluate physician and patient perceptions of symptom burden and impact in women experiencing VMS while receiving EA therapy for breast cancer.
背景:乳腺癌治疗后接受内分泌辅助(EA)治疗的妇女报告了包括血管舒缩症状(VMS)在内的绝经期症状的高发率。VMS影响生活质量,可导致治疗中断和生存率降低,但现有的评估症状负担和影响的文献有限。绝经期妇女血管舒缩和其他症状的真实世界证据(realize)研究旨在评估医生和患者对在接受乳腺癌EA治疗时经历VMS的妇女的症状负担和影响的看法。
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引用次数: 0
Would be mandatory Fragile X syndrome screening in Premature Ovarian Insufficiency study? 在卵巢功能不全研究中是否强制进行脆性X综合征筛查?
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.243
Elisabet Robert Marchal, Beatriz Roca Comella, Sandra Rodriguez Veret, Laia Sánchez Paniagua, Maria Jose Gamundi Rodriguez
Fragile X Syndrome is a confirmed cause of Primary Ovarian Insufficiency (POI). The frequency of women who carry a premutation is 1/300. This has many consequences with the most significant being the loss of reproductive hormones and infertility. However, there are 5-10% of spontaneous pregnancies. For this reason patients must be informed by genetic counselling of the risk of having a newborn who may carry a premutation or Fragile X Syndrome. We report the case of 33-year-old woman referred for 5-month-long amenorrhea. In the study, serum gonadotropins were found at menopausal range. The patient became pregnant without medical intervention and before having the results of the genetic study, which was diagnostic of carrier of Fragile X Syndrome premutation with 90 expanded CGG repeats. An amniocentesis was performed afterwards, which reported the 46XX newborn to be positive for complete mutation of Fragile X Syndrome, with 200 expanded CGG repeats. Finally, a girl with correct weight was born by vaginal delivery at 37.5 weeks. She presented late and slow psychomotor development in the first years of life and is currently receiving paediatric neurology follow-up.
脆性X染色体综合征是原发性卵巢功能不全(POI)的确诊病因。女性携带先兆突变的几率是1/300。这有许多后果,最重要的是生殖激素的丧失和不孕。然而,有5-10%的自然怀孕。因此,患者必须通过遗传咨询了解其新生儿可能携带突变前兆或脆性X综合征的风险。我们报告的情况下,33岁的妇女转介5个月之久的闭经。在研究中,血清促性腺激素在更年期范围内被发现。患者在没有医疗干预的情况下怀孕,在遗传研究结果出来之前,诊断为脆性X综合征前兆突变携带者,扩增了90个CGG重复序列。随后进行羊膜穿刺术,报告46XX新生儿脆性X综合征完全突变阳性,有200个扩增CGG重复序列。最后,一个体重正常的女孩在37.5周时通过阴道分娩出生了。她在生命的头几年表现出晚而缓慢的精神运动发展,目前正在接受儿科神经病学随访。
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引用次数: 0
A case report - Multidisciplinary approach to sexual dysfunction in post-menopausal women in Singapore 一例报告-多学科方法在新加坡绝经后妇女性功能障碍
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.158
Jean Jasmin Lee, Farah Safdar, Seng Bin Ang
Introduction & Rationale: This case highlights the multidisciplinary approach used in the management of sexual dysfunction in post-menopausal women. A 52-year-old Chinese female presented with an 8-month history of worsening dyspareunia, low libido and secondary anorgasmia. She was on continuous menopause hormone therapy (MHT) that was initiated 2 years prior. Her initial presenting complaints were hot flushes, sleep disruption, vaginal dryness and mood instability – all of which resolved with MHT. She was found to have secondary vaginismus contributed by stressors that perpetuated the sexual dysfunction cycle. Predisposing factors included mild stress incontinence since the birth of her second child 18 years ago and work-related stress. Psycho-social factors included anxiety about not being able to satisfy her husband’s sexual needs leading to his infidelity, and the impact on her marriage.
本病例强调了多学科方法在绝经后妇女性功能障碍治疗中的应用。52岁中国女性,有8个月性交困难加重、性欲低下和继发性性高潮障碍病史。她在2年前开始持续接受更年期激素治疗(MHT)。她最初的症状是潮热、睡眠中断、阴道干燥和情绪不稳定——所有这些都通过MHT解决了。她被发现有继发性阴道痉挛,这是由持续性功能障碍循环的压力源引起的。诱发因素包括18年前生下第二胎后的轻度压力性尿失禁和工作压力。心理社会因素包括无法满足丈夫的性需求而导致他不忠的焦虑,以及对她婚姻的影响。
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引用次数: 0
Vaginal Erbium Laser as a non-hormonal therapeutical procedure for managing urinary symptoms in breast and gynecological cancer survivors 阴道铒激光作为一种非激素治疗程序,用于管理乳腺癌和妇科癌症幸存者的泌尿系统症状
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.172
Vittoria Frisetti Carpani, Giulia Misasi, Maria Magdalena Montt Guevara, Cristina Zito, Eleonora Russo, Tommaso Simoncini
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引用次数: 0
Early menopause and premature ovarian insufficiency may increase the risk of sarcopenia: a systematic review and meta-analysis 早期绝经和卵巢功能不全可能增加肌肉减少症的风险:一项系统回顾和荟萃分析
Pub Date : 2023-07-01 DOI: 10.1016/j.maturitas.2023.04.075
Efstathios Divaris, Panagiotis Anagnostis, Nifon Gkekas, Evangelia Kouidi, Dimitrios Goulis
{"title":"Early menopause and premature ovarian insufficiency may increase the risk of sarcopenia: a systematic review and meta-analysis","authors":"Efstathios Divaris, Panagiotis Anagnostis, Nifon Gkekas, Evangelia Kouidi, Dimitrios Goulis","doi":"10.1016/j.maturitas.2023.04.075","DOIUrl":"https://doi.org/10.1016/j.maturitas.2023.04.075","url":null,"abstract":"","PeriodicalId":94131,"journal":{"name":"Maturitas","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135154694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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