Revolutionizing Medicine: The Promise of Camouflage Nanoparticles - A Review

Q3 Materials Science Current Nanomaterials Pub Date : 2023-10-25 DOI:10.2174/0124054615273067231011110436
Vajagathali Mohammed, Nikitha Shalom Richard
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Abstract

Abstract: Camouflage nanoparticles (CNPs) have emerged as a promising paradigm in the realm of disease therapy, offering a distinctive set of properties and versatile applications. These nanoparticles, characterized by their size, typically falling within the range of 1 to 100 nm, hold significant promise for the realms of targeted drug delivery, diagnostics, and imaging. Diverse categories of camouflage nanoparticles, encompassing liposomes, polymeric nanoparticles, and dendrimers, have been under intensive scrutiny for their potential to combat a spectrum of diseases, including neurological disorders, cardiovascular ailments, genetic anomalies, and cancer. These nanoparticles exhibit the remarkable ability to surmount biological barriers, including the formidable blood-brain barrier, thereby facilitating the precise delivery of therapeutic agents to specific cells or tissues. This precision augments drug efficacy while simultaneously mitigating systemic side effects. Nevertheless, challenges persist in the refinement of nanoparticle design, the assurance of long-term safety, and the pursuit of scalability and cost-effectiveness. Looking ahead, future prospects encompass expanding the purview of disease-specific applications, advancing cutting-edge imaging modalities, crafting multifunctional nanoparticles, and seamlessly integrating nascent technologies. With relentless dedication to research and innovation, CNPs hold the potential to metamorphose the landscape of disease therapy, ushering in a new era marked by heightened drug efficacy, diminished side effects, and the realization of personalized medicine paradigms. This review aims to illuminate the burgeoning arena of CNPs in disease therapy, casting a spotlight on their latent potential as a conduit for targeted drug delivery. Through an exploration of their unique attributes, applications, and extant challenges, this review seeks to galvanize further research and development within this propitious domain, ultimately striving to revolutionize disease therapy by aligning it with the tenets of enhanced efficacy, attenuated side effects, and the realization of personalized medicine aspirations.
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医学革命:伪装纳米粒子的前景-综述
摘要:伪装纳米粒子(CNPs)已成为疾病治疗领域的一个有前途的范例,提供了一套独特的特性和广泛的应用。这些纳米颗粒的特点是它们的大小,通常在1到100纳米的范围内,在靶向药物输送、诊断和成像领域具有重要的前景。各种各样的伪装纳米颗粒,包括脂质体、聚合纳米颗粒和树状大分子,已经受到了密切的关注,因为它们具有对抗一系列疾病的潜力,包括神经系统疾病、心血管疾病、基因异常和癌症。这些纳米颗粒表现出克服生物屏障的非凡能力,包括强大的血脑屏障,从而促进治疗剂精确地输送到特定的细胞或组织。这种精确性增强了药物功效,同时减轻了全身副作用。然而,在纳米颗粒设计的改进、长期安全性的保证以及对可扩展性和成本效益的追求方面,挑战仍然存在。展望未来,未来的前景包括扩大特定疾病的应用范围,推进尖端的成像模式,制作多功能纳米颗粒,以及无缝整合新兴技术。随着对研究和创新的不懈投入,CNPs有可能改变疾病治疗的格局,开创一个以提高药物疗效、减少副作用和实现个性化医疗范例为标志的新时代。本综述旨在阐明CNPs在疾病治疗中的新兴领域,聚焦其作为靶向药物输送管道的潜在潜力。通过对其独特属性、应用和现存挑战的探索,本综述旨在激发这一有利领域的进一步研究和开发,最终努力通过将其与增强疗效、减少副作用和实现个性化医疗愿望的原则相结合,彻底改变疾病治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Nanomaterials
Current Nanomaterials Materials Science-Materials Science (miscellaneous)
CiteScore
1.60
自引率
0.00%
发文量
53
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