Serum Obestatin Levels in PCOS and its Relation with Homa-IR

Tarique Aziz, Charu Gunjal, G G Kaushik
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 Patients and methods: We analyzed 30 patients with PCOS and 20 normal women as controls. PCOS patients were divided into two groups based on obese group and non-obese group Serum Obestatin levels, Insulin Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) determined and compared among both groups.
 Results: Serum Obestatin levels were significantly lower in obese PCOS group than non-obese and control.","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"38 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical and Biomedical Studies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32553/ijmbs.v7i8.2740","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Background: Is to investigate the level of Obestatin in PCOS patients and compare with controls and also see the correlations between the serum Obestatin levels and HOMA-IR. Patients and methods: We analyzed 30 patients with PCOS and 20 normal women as controls. PCOS patients were divided into two groups based on obese group and non-obese group Serum Obestatin levels, Insulin Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) determined and compared among both groups. Results: Serum Obestatin levels were significantly lower in obese PCOS group than non-obese and control.
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PCOS患者血清肥胖抑制素水平及其与Homa-IR的关系
背景:目的是研究PCOS患者的Obestatin水平,并与对照组进行比较,同时观察血清Obestatin水平与HOMA-IR的相关性。 患者和方法:我们分析了30例PCOS患者和20例正常女性作为对照。将多囊卵巢综合征(PCOS)患者分为肥胖组和非肥胖组,测定血清obstatin水平、胰岛素稳态模型评估胰岛素抵抗(HOMA-IR),并比较两组间的差异。 结果:肥胖PCOS组血清obstatin水平明显低于非肥胖组和对照组。
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