Background: Amenorrhea, defined as the absence of menstruation, is a symptom indicative of underlying health issues rather than a disease itself. Secondary amenorrhea is characterized by the cessation of established menstruation for six months or longer, or alternatively, previously regular menses for three months or previously irregular menses for six months. The incidence of secondary amenorrhea is estimated to be 3% to 4% among women in the general population. Aim: This study aims to evaluate the etiology, diagnostic approaches, and management strategies for secondary amenorrhea among patients presenting to the gynecology outpatient department at MKCG Medical College, Berhampur, Odisha, India. Methods: A total of 25 patients diagnosed with secondary amenorrhea were included in this study. A comprehensive evaluation was conducted, including detailed medical history, physical examination, laboratory investigations (hormonal profile, thyroid function tests, prolactin levels), and imaging studies (ultrasound, MRI). Management strategies were individualized based on the etiology and included medical, surgical, and lifestyle interventions. Results: The study identified various etiologies for secondary amenorrhea, including hormonal imbalances, structural abnormalities, and systemic conditions. The individualized management plans led to successful outcomes in most cases, with resumption of menstruation and improvement in symptoms. Specific cases highlighted include prolactinoma, PCOS, premature ovarian insufficiency, and Asherman’s syndrome, each requiring distinct diagnostic and therapeutic approaches. Conclusion: Secondary amenorrhea presents with diverse etiologies, necessitating a thorough and multidisciplinary approach for diagnosis and management. Early and accurate diagnosis, along with tailored interventions, are crucial for effective treatment and improved patient outcomes. Recommendations: Implementation of standardized protocols for the evaluation of secondary amenorrhea in clinical practice. Encourage multidisciplinary collaboration for the management of complex cases. Promote patient education regarding the potential causes and treatments for secondary amenorrhea. Conduct further research to explore long-term outcomes of various management strategies.Enhance awareness among healthcare providers about the importance of early intervention. Keywords: Secondary Amenorrhea, Hormonal Imbalance, PCOS, Premature Ovarian Insufficiency, Tertiary Care
{"title":"Evaluation and Management of Secondary Amenorrhea: A Case Series in a Tertiary Care Centre","authors":"Abhishek Behera, Suchismita Panda, Arun Kumar Choudhary, Mahija Sahu","doi":"10.32553/ijmbs.v8i3.2821","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2821","url":null,"abstract":"Background: Amenorrhea, defined as the absence of menstruation, is a symptom indicative of underlying health issues rather than a disease itself. Secondary amenorrhea is characterized by the cessation of established menstruation for six months or longer, or alternatively, previously regular menses for three months or previously irregular menses for six months. The incidence of secondary amenorrhea is estimated to be 3% to 4% among women in the general population. \u0000Aim: This study aims to evaluate the etiology, diagnostic approaches, and management strategies for secondary amenorrhea among patients presenting to the gynecology outpatient department at MKCG Medical College, Berhampur, Odisha, India. \u0000Methods: A total of 25 patients diagnosed with secondary amenorrhea were included in this study. A comprehensive evaluation was conducted, including detailed medical history, physical examination, laboratory investigations (hormonal profile, thyroid function tests, prolactin levels), and imaging studies (ultrasound, MRI). Management strategies were individualized based on the etiology and included medical, surgical, and lifestyle interventions. \u0000Results: The study identified various etiologies for secondary amenorrhea, including hormonal imbalances, structural abnormalities, and systemic conditions. The individualized management plans led to successful outcomes in most cases, with resumption of menstruation and improvement in symptoms. Specific cases highlighted include prolactinoma, PCOS, premature ovarian insufficiency, and Asherman’s syndrome, each requiring distinct diagnostic and therapeutic approaches. \u0000Conclusion: Secondary amenorrhea presents with diverse etiologies, necessitating a thorough and multidisciplinary approach for diagnosis and management. Early and accurate diagnosis, along with tailored interventions, are crucial for effective treatment and improved patient outcomes. \u0000Recommendations: \u0000Implementation of standardized protocols for the evaluation of secondary amenorrhea in clinical practice. Encourage multidisciplinary collaboration for the management of complex cases. Promote patient education regarding the potential causes and treatments for secondary amenorrhea. Conduct further research to explore long-term outcomes of various management strategies.Enhance awareness among healthcare providers about the importance of early intervention. \u0000Keywords: Secondary Amenorrhea, Hormonal Imbalance, PCOS, Premature Ovarian Insufficiency, Tertiary Care","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-17DOI: 10.32553/ijmbs.v8i3.2820
Kumar Himanshu, Abdur Rahman Al Adil, Abhay Kumar
Background: Type 2 Diabetes Mellitus (T2DM) and Impaired Glucose Tolerance (IGT) are major public health concerns globally, with increasing prevalence in India. The study assessed the prevalence of T2DM and IGT among, and to recognize key associated risk factors. Methods: 1050 persons were involved in the study selected by rigorous random sampling. To diagnose T2DM and IGT, data were gathered via in-person interviews using a pre-made questionnaire, which were then followed by clinical exams and blood testing. Results: The incidence of IGT was 12.48% and T2DM was 9.24%, respectively. In the 61–70 age range, the highest incidence of T2DM (20.86%) and IGT (21.58%) was noted. The incidence of T2DM was somewhat higher in men (9.87%) than in women (8.58%). The incidence rates of T2DM (21.84%) and IGT (36.78%) were considerably greater in those with a positive family record of diabetes. Additionally, there was a substantial correlation found between obesity and hypertension and a higher incidence of T2DM and IGT. Conclusion: The study reveals a considerable incidence of T2DM and IGT in the Sharifganj area of Katihar, with advanced age, male gender, family history of diabetes, obesity, and hypertension identified as key risk factors. Recommendations: Targeted public health interventions, including lifestyle modifications, regular screenings, and health education, are essential to manage and reduce the risk of diabetes in this community. Keywords: Prediabetes,T2DM, Impaired Glucose Tolerance, IGT, Impaired Fasting Glucose, IFG, Risk Factors, Katihar, Bihar.
{"title":"Prevalence of Prediabetes and Associated Risk Factor Assessment Among Urban Adult Population in North Bihar, India","authors":"Kumar Himanshu, Abdur Rahman Al Adil, Abhay Kumar","doi":"10.32553/ijmbs.v8i3.2820","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2820","url":null,"abstract":"Background: Type 2 Diabetes Mellitus (T2DM) and Impaired Glucose Tolerance (IGT) are major public health concerns globally, with increasing prevalence in India. The study assessed the prevalence of T2DM and IGT among, and to recognize key associated risk factors. \u0000Methods: 1050 persons were involved in the study selected by rigorous random sampling. To diagnose T2DM and IGT, data were gathered via in-person interviews using a pre-made questionnaire, which were then followed by clinical exams and blood testing. \u0000Results: The incidence of IGT was 12.48% and T2DM was 9.24%, respectively. In the 61–70 age range, the highest incidence of T2DM (20.86%) and IGT (21.58%) was noted. The incidence of T2DM was somewhat higher in men (9.87%) than in women (8.58%). The incidence rates of T2DM (21.84%) and IGT (36.78%) were considerably greater in those with a positive family record of diabetes. Additionally, there was a substantial correlation found between obesity and hypertension and a higher incidence of T2DM and IGT. \u0000Conclusion: The study reveals a considerable incidence of T2DM and IGT in the Sharifganj area of Katihar, with advanced age, male gender, family history of diabetes, obesity, and hypertension identified as key risk factors. \u0000Recommendations: Targeted public health interventions, including lifestyle modifications, regular screenings, and health education, are essential to manage and reduce the risk of diabetes in this community. \u0000Keywords: Prediabetes,T2DM, Impaired Glucose Tolerance, IGT, Impaired Fasting Glucose, IFG, Risk Factors, Katihar, Bihar.","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.32553/ijmbs.v8i4.2819
Atikah Mawardhani Putri, S. Adiantoro, Harmas Yazid
Introduction: Squamous cell carcinoma is the most common malignant neoplasm in the oral cavity, accounting for 90% of all malignancies in the oral cavity. Exposure of the oral epithelium to carcinogenic substances can cause squamous cell carcinoma. This study was show the prevalence of squamous cell carcinoma of the tongue in West Java which is used as education for the prevention of squamous cell carcinoma of the tongue. Purpose: This research is a descriptive study and carried out using purposive sampling method. The sample in this study were patients with a diagnosis of squamous cell carcinoma of the tongue at Dr. Hasan Sadikin Hospital Bandung during January 2017 - January 2022 who had been confirmed by histopathological examination results. Data analysis will be carried out on secondary data from collected medical records and the results of the pathologist's interpretation, then the results of the data analysis will be arranged and presented in tabular and percentage form. Methods: The data obtained were 218 cases. Based on age, the most patients were in the age group above 48 years (58%). Based on gender criteria, it shows more women (57%). Based on domicile criteria, the highest domicile was in Bandung (38%). Based on family history criteria, there were 215 patients with no family history or 99%. Based on the predisposing factor criteria, it shows more patients with a history of chronic irritation (48%). Based on the mass size criteria, it shows more patients with mass size T4 (60%). Based on KGB criteria, it shows more patient showed N1 lymph nodes involvement (63%). Based on tumor metastasis criteria, it shows more patients with Mx tumor metastasis (50%). Based on the therapy status criteria, it shows more patients with combined therapy (32%). Results: Type the result of your research, including statistical analysis. Conclusion: Patients suffering from squamous cell carcinoma in the tongue are mostly patients over 48 years old with female gender who live in Bandung City, West Java, and have no family history but have predilection factors such as irritation and infection. The size of the tumor mass in patients with squamous cell carcinoma mostly has a mass size > 3 cm, with lymph node involvement mostly on the ipsilateral with a size < 3 cm and metastasis to other organs is difficult to assess due to lack of supporting modalities. The therapy received was mostly combined therapy (surgery and chemotherapy or radiotherapy) Keywords: Squamous cell carcinoma of the tongue, prevalence, patient characteristics
{"title":"Prevalence of Squamous Cell Carcinoma of The Tongue In Dr. Hasan Sadikin General Hospital During 2017 – 2022","authors":"Atikah Mawardhani Putri, S. Adiantoro, Harmas Yazid","doi":"10.32553/ijmbs.v8i4.2819","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i4.2819","url":null,"abstract":"Introduction: Squamous cell carcinoma is the most common malignant neoplasm in the oral cavity, accounting for 90% of all malignancies in the oral cavity. Exposure of the oral epithelium to carcinogenic substances can cause squamous cell carcinoma. This study was show the prevalence of squamous cell carcinoma of the tongue in West Java which is used as education for the prevention of squamous cell carcinoma of the tongue. \u0000Purpose: This research is a descriptive study and carried out using purposive sampling method. The sample in this study were patients with a diagnosis of squamous cell carcinoma of the tongue at Dr. Hasan Sadikin Hospital Bandung during January 2017 - January 2022 who had been confirmed by histopathological examination results. Data analysis will be carried out on secondary data from collected medical records and the results of the pathologist's interpretation, then the results of the data analysis will be arranged and presented in tabular and percentage form. \u0000Methods: The data obtained were 218 cases. Based on age, the most patients were in the age group above 48 years (58%). Based on gender criteria, it shows more women (57%). Based on domicile criteria, the highest domicile was in Bandung (38%). Based on family history criteria, there were 215 patients with no family history or 99%. Based on the predisposing factor criteria, it shows more patients with a history of chronic irritation (48%). Based on the mass size criteria, it shows more patients with mass size T4 (60%). Based on KGB criteria, it shows more patient showed N1 lymph nodes involvement (63%). Based on tumor metastasis criteria, it shows more patients with Mx tumor metastasis (50%). Based on the therapy status criteria, it shows more patients with combined therapy (32%). \u0000Results: Type the result of your research, including statistical analysis. \u0000Conclusion: Patients suffering from squamous cell carcinoma in the tongue are mostly patients over 48 years old with female gender who live in Bandung City, West Java, and have no family history but have predilection factors such as irritation and infection. The size of the tumor mass in patients with squamous cell carcinoma mostly has a mass size > 3 cm, with lymph node involvement mostly on the ipsilateral with a size < 3 cm and metastasis to other organs is difficult to assess due to lack of supporting modalities. The therapy received was mostly combined therapy (surgery and chemotherapy or radiotherapy) \u0000Keywords: Squamous cell carcinoma of the tongue, prevalence, patient characteristics","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141646205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-11DOI: 10.32553/ijmbs.v8i3.2815
Tushar Kante Behera, Bibekananda Nayak, Biswaranjan Panda
Background: The correlation between thyroid autoimmunity and cerebrovascular diseases, particularly intracranial stenosis, is increasingly recognized. Early-onset stroke, occurring in individuals under 50 years, often involves non-traditional risk factors, including autoimmune disorders. Elevated thyroid autoantibodies, such as thyroid peroxidase (TPO) and thyroglobulin (TG) antibodies, have been implicated in vascular abnormalities. In patients with early-onset stroke, the study aims to investigate into the relationship between increased thyroid autoantibodies and intracranial stenosis. Methods: A retrospective cohort study included 180 patients diagnosed with early-onset stroke. Data were collected from medical records, focusing on thyroid function tests, thyroid autoantibody levels, and imaging results for intracranial stenosis. Multivariate logistic regression, t-tests, and chi-square tests were used in the statistical analysis to determine whether higher thyroid autoantibodies independently caused intracranial stenosis. Results: Intracranial stenosis was present in 40% of the patients. Elevated TPO antibodies were found in 62.5% of patients with intracranial stenosis compared to 25.0% without (p<0.001). Elevated TG antibodies were present in 54.2% of patients with intracranial stenosis compared to 25.0% without (p<0.001). Univariate analysis showed that elevated TPO antibodies (OR=4.75) and elevated TG antibodies (OR=3.44) were significantly associated with intracranial stenosis. Multivariate logistic regression confirmed these associations, with adjusted odds ratios of 4.23 for TPO and 3.16 for TG antibodies. Conclusion: Elevated thyroid autoantibodies are significantly related with an elevated risk of intracranial stenosis in early-onset stroke patients. This suggests that thyroid autoimmunity plays a critical role in the pathogenesis of intracranial vascular abnormalities. Recommendations: Routine screening for thyroid autoantibodies in young stroke patients is recommended to identify those at higher risk for intracranial stenosis. Further research is needed to explore the mechanisms linking thyroid autoimmunity to vascular abnormalities and to develop targeted therapeutic strategies. Keywords: Thyroid Autoantibodies, Intracranial Stenosis, Early-Onset Stroke, Thyroid Peroxidase Antibodies, Thyroglobulin Antibodies
{"title":"Elevated Thyroid Autoantibodies and Intracranial Stenosis in Early-Onset Stroke","authors":"Tushar Kante Behera, Bibekananda Nayak, Biswaranjan Panda","doi":"10.32553/ijmbs.v8i3.2815","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2815","url":null,"abstract":"Background: The correlation between thyroid autoimmunity and cerebrovascular diseases, particularly intracranial stenosis, is increasingly recognized. Early-onset stroke, occurring in individuals under 50 years, often involves non-traditional risk factors, including autoimmune disorders. Elevated thyroid autoantibodies, such as thyroid peroxidase (TPO) and thyroglobulin (TG) antibodies, have been implicated in vascular abnormalities. In patients with early-onset stroke, the study aims to investigate into the relationship between increased thyroid autoantibodies and intracranial stenosis. \u0000Methods: A retrospective cohort study included 180 patients diagnosed with early-onset stroke. Data were collected from medical records, focusing on thyroid function tests, thyroid autoantibody levels, and imaging results for intracranial stenosis. Multivariate logistic regression, t-tests, and chi-square tests were used in the statistical analysis to determine whether higher thyroid autoantibodies independently caused intracranial stenosis. \u0000Results: Intracranial stenosis was present in 40% of the patients. Elevated TPO antibodies were found in 62.5% of patients with intracranial stenosis compared to 25.0% without (p<0.001). Elevated TG antibodies were present in 54.2% of patients with intracranial stenosis compared to 25.0% without (p<0.001). Univariate analysis showed that elevated TPO antibodies (OR=4.75) and elevated TG antibodies (OR=3.44) were significantly associated with intracranial stenosis. Multivariate logistic regression confirmed these associations, with adjusted odds ratios of 4.23 for TPO and 3.16 for TG antibodies. \u0000Conclusion: Elevated thyroid autoantibodies are significantly related with an elevated risk of intracranial stenosis in early-onset stroke patients. This suggests that thyroid autoimmunity plays a critical role in the pathogenesis of intracranial vascular abnormalities. \u0000Recommendations: Routine screening for thyroid autoantibodies in young stroke patients is recommended to identify those at higher risk for intracranial stenosis. Further research is needed to explore the mechanisms linking thyroid autoimmunity to vascular abnormalities and to develop targeted therapeutic strategies. \u0000Keywords: Thyroid Autoantibodies, Intracranial Stenosis, Early-Onset Stroke, Thyroid Peroxidase Antibodies, Thyroglobulin Antibodies","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"122 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical diagnosis of Pemphigus and Bullous pemphigoid relies heavily on the appearance of the bulla which varies depending on multiple factors like age of the lesion, itching, previous or self application of steroids, and most importantly skin tone. Most of the medical literature is derived from studies in the western population and hence leaves a large gap in the knowledge of presentation of these diseases in the Indian population. An accurate representation of these varied clinical presentations is required to enable the clinicians to make a competent diagnosis..
{"title":"Pemphigus and Bullous Pemphigoid in Indian Skin: A Study done in Tertiary Hospital of Bihar","authors":"Sneha Sinha, Pallavi Mehra, Sneha Aditi, Dilip Kumar","doi":"10.32553/ijmbs.v8i3.2814","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2814","url":null,"abstract":"\u0000 \u0000 \u0000Clinical diagnosis of Pemphigus and Bullous pemphigoid relies heavily on the appearance of the bulla which varies depending on multiple factors like age of the lesion, itching, previous or self application of steroids, and most importantly skin tone. Most of the medical literature is derived from studies in the western population and hence leaves a large gap in the knowledge of presentation of these diseases in the Indian population. An accurate representation of these varied clinical presentations \u0000is required to enable the clinicians to make a competent diagnosis.. \u0000 \u0000 \u0000","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"18 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Bone lesions have low incidence with diverse presentation and due to the presence of their limited studies it has become a challenging task to reach an accurate diagnosis. Aim and Objective: This study aims in studying variety of bony lesions observed clinically and histopathologically. Further categorizing into non neoplastic, tumour-like, benign tumour or malignant tumour and determining its correlation with the age and gender predisposition of these lesions. Materials and Methods: An ambispective study was executed in Pathology department , PMCH, Patna from May 2020 to April 2024 in which a total of 102 cases were collected. The necessary information for the retrospective analysis, such as the patient's age, sex, lesion location, and diagnosis, was obtained from the requisition form and the histopathology data kept in the department of pathology from May 2020 to May 2022. And for prospective study all the radiological proven bony lesions which were excised during period of May 2022 to April 2024 and were sent for histopathological examination were examined. Results: Non-neoplastic lesions were more common than neoplastic lesions among the 102 specimens that underwent histological examination (53 versus 49). With 21.5% of cases, tuberculous osteomyelitis was the most prevalent non-neoplastic lesion. The most common benign neoplastic lesion detected was a giant cell tumor of the bone (11.76%), while the most common malignant lesion found was osteosarcoma (2.94%). Conclusion: To improve patient management and diagnosis accuracy, it is advised to utilize clinical, radiological, and histological findings in an integrated manner.
{"title":"Pink and Blue of Bones- A Histopathological Analysis of Bony Neoplasm in a Tertiary Hospital of Bihar","authors":"Aishwarya Krishna, Pallavi Mehra, Sneha Aditi, Dilip Kumar","doi":"10.32553/ijmbs.v8i3.2812","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2812","url":null,"abstract":"Background: Bone lesions have low incidence with diverse presentation and due to the presence of their limited studies it has become a challenging task to reach an accurate diagnosis. \u0000Aim and Objective: This study aims in studying variety of bony lesions observed clinically and histopathologically. Further categorizing into non neoplastic, tumour-like, benign tumour or malignant tumour and determining its correlation with the age and gender predisposition of these lesions. \u0000Materials and Methods: An ambispective study was executed in Pathology department , PMCH, Patna from May 2020 to April 2024 in which a total of 102 cases were collected. The necessary information for the retrospective analysis, such as the patient's age, sex, lesion location, and diagnosis, was obtained from the requisition form and the histopathology data kept in the department of pathology from May 2020 to May 2022. \u0000And for prospective study all the radiological proven bony lesions which were excised during period of May 2022 to April 2024 and were sent for histopathological examination were examined. \u0000Results: Non-neoplastic lesions were more common than neoplastic lesions among the 102 specimens that underwent histological examination (53 versus 49). With 21.5% of cases, tuberculous osteomyelitis was the most prevalent non-neoplastic lesion. The most common benign neoplastic lesion detected was a giant cell tumor of the bone (11.76%), while the most common malignant lesion found was osteosarcoma (2.94%). \u0000Conclusion: To improve patient management and diagnosis accuracy, it is advised to utilize clinical, radiological, and histological findings in an integrated manner.","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.32553/ijmbs.v8i3.2790
Atikah Mawardhani Putri, M. Sylvyana, H. Yusuf
Introduction : Facial trauma can be defined as bone and or soft tissue damage in the face region. Severe facial trauma might cause life threatening and permanent damage such as vision loss, unable to speak, swallows and chews because there are many bones, blood vessels, nerves, muscles and sensory organs at the face region. The facial damage could be a facial bone fracture with severe avulsion of facial tissue so two-dimensional and three-dimensional measurement of the wound is taken to assess the size of tissue to be covered. The aim of this case report was to give an explanation regarding the emergency management patient with multiple mid-lower face fracture and tissue avulsion of 1/3 mid face. Case Report : A 46 years old male traffic accident patient came to Emergency Department Hasan Sadikin General Hospital with facial fracture and had a severe avulsion of facial tissue. He also had an active bleeding from his face and based on immediate examination the airway was not clear. The patient has been diagnosed with Le Fort I, right orbital rim inferior aspect, nasal, right zygoma and parasymphisis of mandible bone fracture and Tissue loss at upper lip, nasolabial, left nose, left buccal and Multiple lacerated wound at facial region. He was treated with tracheostomy to clear the airway continued with open reduction internal fixation at right orbital rim inferior aspect, nasal, right zygoma, bilateral maxilla bone and parasymphisis of mandible bone with wound closing using rotational and sliding loco regional flap technique. Conclusion : Emergency treatment on multiple facial fracture with severe avulsion of facial tissue must be done to prevent life threatening condition, permanent damage and also to support the secondary reconstruction. Keywords : Severe avulsion of facial tissue, Mid lower face fracture, Open reduction internal fixation, Rotational flap, Sliding loco regional flap
简介 ：面部创伤可定义为面部区域的骨骼和软组织损伤。由于面部区域有许多骨骼、血管、神经、肌肉和感觉器官，严重的面部创伤可能会导致视力丧失、无法说话、吞咽和咀嚼等危及生命的永久性损伤。面部损伤可能是面部骨骼骨折，面部组织严重撕脱，因此需要对伤口进行二维和三维测量，以评估需要覆盖的组织的大小。本病例报告的目的是解释如何紧急处理面部中下部多处骨折和 1/3 中面部组织撕脱的患者。病例报告：一名 46 岁的男性交通事故患者因面部骨折和面部组织严重撕脱来到 Hasan Sadikin 综合医院急诊科。他的脸部还在出血，根据即时检查，呼吸道并不通畅。患者被诊断为 Le Fort I、右眼眶边缘下侧、鼻腔、右颧骨和下颌骨旁骨折，上唇、鼻唇、左鼻、左颊部组织缺失，面部多处撕裂伤。他接受了气管插管术以疏通气道，然后在右眶缘下侧、鼻翼、右侧颧骨、双侧上颌骨和下颌骨副韧带处进行了切开复位内固定术，并使用旋转和滑动局部区域皮瓣技术缝合了伤口。结论：必须对面部组织严重撕脱的多发性面部骨折进行紧急治疗，以防止危及生命的情况、永久性损伤以及支持二次重建。 关键词：面部组织严重撕脱 面部中下段骨折 开放复位内固定 旋转皮瓣 滑动区域皮瓣
{"title":"Emergency Management Patient with Multiple Mid-Lower Face Fracture and Tissue Avulsion of 1/3 Mid Face : A Case Report","authors":"Atikah Mawardhani Putri, M. Sylvyana, H. Yusuf","doi":"10.32553/ijmbs.v8i3.2790","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2790","url":null,"abstract":"Introduction : Facial trauma can be defined as bone and or soft tissue damage in the face region. Severe facial trauma might cause life threatening and permanent damage such as vision loss, unable to speak, swallows and chews because there are many bones, blood vessels, nerves, muscles and sensory organs at the face region. The facial damage could be a facial bone fracture with severe avulsion of facial tissue so two-dimensional and three-dimensional measurement of the wound is taken to assess the size of tissue to be covered. The aim of this case report was to give an explanation regarding the emergency management patient with multiple mid-lower face fracture and tissue avulsion of 1/3 mid face.\u0000Case Report : A 46 years old male traffic accident patient came to Emergency Department Hasan Sadikin General Hospital with facial fracture and had a severe avulsion of facial tissue. He also had an active bleeding from his face and based on immediate examination the airway was not clear. The patient has been diagnosed with Le Fort I, right orbital rim inferior aspect, nasal, right zygoma and parasymphisis of mandible bone fracture and Tissue loss at upper lip, nasolabial, left nose, left buccal and Multiple lacerated wound at facial region. He was treated with tracheostomy to clear the airway continued with open reduction internal fixation at right orbital rim inferior aspect, nasal, right zygoma, bilateral maxilla bone and parasymphisis of mandible bone with wound closing using rotational and sliding loco regional flap technique.\u0000Conclusion : Emergency treatment on multiple facial fracture with severe avulsion of facial tissue must be done to prevent life threatening condition, permanent damage and also to support the secondary reconstruction.\u0000Keywords : Severe avulsion of facial tissue, Mid lower face fracture, Open reduction internal fixation, Rotational flap, Sliding loco regional flap","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"40 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-02DOI: 10.32553/ijmbs.v8i3.2791
Marissa Adelina, E. Sjamsudin, M. Sylvyana
Background: Necrotizing fasciitis (NF) is a relatively rare infectious disease of soft tissues that is characterized by necrosis of subcutaneous tissue and fascia and can even extend to involve the skin and muscles, with the main spread through odontogenic infections. One of the main comorbidities of necrotizing fasciitis is diabetes mellitus. Proper case management is needed because NF can result in severe morbidity and mortality if not treated at an early stage. Study Objective: This case report aims to report the management of patients with buccal necrotizing fasciitis complicated by submandibular abscesses with comorbid type 2 diabetes mellitus. Case Presentation: A 60-year-old woman came to RSHS complaining of swelling on her right cheek 20 days before hospital admission, which further extended to the jaw and neck area. Swelling on the patient's face did not improve after antibiotic treatment, and continued to enlarge to a size of 10x8x7 cm and 8x6x5 cm. The patient has a history of type 2 diabetes mellitus and controlled hypertension. The patient is diagnosed as necrotizing fasciitis and submandibular abscess. Patients are given antibiotic treatment and performed pus-tapping, necrotomy debridement, and tooth extraction. Conclusion : Necrotizing fasciitis involving the facial (especially buccal) area is rare, with the main cause being odontogenic, peritonsillar, or sinugenic. The main management includes debridement, reconstructive measures, and administration of antibiotics. Extensive tissue involvement, and poly-comorbid conditions can worsen the prognosis of necrotizing fasciitis. Keywords : Abscess, Buccal, Colli dextra, Necrotizing fasciitis, Submandibular
{"title":"Management of Unilateral Buccal Necrotizing Fasciitis Superimposed with Submandibular Abscess At Colli Dextra in a Type 2 Diabetes Mellitus patient : A Case Report","authors":"Marissa Adelina, E. Sjamsudin, M. Sylvyana","doi":"10.32553/ijmbs.v8i3.2791","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2791","url":null,"abstract":"Background: Necrotizing fasciitis (NF) is a relatively rare infectious disease of soft tissues that is characterized by necrosis of subcutaneous tissue and fascia and can even extend to involve the skin and muscles, with the main spread through odontogenic infections. One of the main comorbidities of necrotizing fasciitis is diabetes mellitus. Proper case management is needed because NF can result in severe morbidity and mortality if not treated at an early stage.\u0000Study Objective: This case report aims to report the management of patients with buccal necrotizing fasciitis complicated by submandibular abscesses with comorbid type 2 diabetes mellitus.\u0000Case Presentation: A 60-year-old woman came to RSHS complaining of swelling on her right cheek 20 days before hospital admission, which further extended to the jaw and neck area. Swelling on the patient's face did not improve after antibiotic treatment, and continued to enlarge to a size of 10x8x7 cm and 8x6x5 cm. The patient has a history of type 2 diabetes mellitus and controlled hypertension. The patient is diagnosed as necrotizing fasciitis and submandibular abscess. Patients are given antibiotic treatment and performed pus-tapping, necrotomy debridement, and tooth extraction.\u0000Conclusion : Necrotizing fasciitis involving the facial (especially buccal) area is rare, with the main cause being odontogenic, peritonsillar, or sinugenic. The main management includes debridement, reconstructive measures, and administration of antibiotics. Extensive tissue involvement, and poly-comorbid conditions can worsen the prognosis of necrotizing fasciitis.\u0000Keywords : Abscess, Buccal, Colli dextra, Necrotizing fasciitis, Submandibular","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"47 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141274071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Women who experience vaginal bleeding in the early stages of their pregnancy should be extremely worried about the phenomenon of "threatened abortion". Predicting the course of a pregnancy and choosing the best management techniques are critical to providing the best possible care for patients. The purpose of this investigation's prospective observational design was to learn more about the predictive power of ultrasound and how it may affect the medical management of upcoming abortions. Method: For the study, 200 first trimester pregnant women who showed indicators of an imminent abortion were gathered between X and Y. We looked at the fetus's heart, the size of the cervical canal, and a few other parts of the gestational sac using ultrasonography. Furthermore, records pertaining to the existence of extra data, like subchorionic hematoma, were found. Numerous exams were conducted to monitor the pregnancy's development. Results: Of the research's participants, 35% miscarried for unidentified reasons, and 65% were able to bring their pregnancies to term. The pregnancy's outcome could be accurately predicted based on the ultrasonography results. More specifically, there was a significant correlation between the development of a visible gestational sac and the presence of fetal heart activity and a higher chance of a successful pregnancy outcome. This was a strong relationship. On the other hand, women who had a subchorionic hematoma or a shorter cervical length were found to have a significantly higher risk of miscarriage. These findings show the value of ultrasonography as a technique for forecasting the course of pregnancies that are at risk of ending because of difficulties connected to the threat of abortion. Conclusion: Investigation's prospective observational design shows how ultrasound can be used to evaluate the advancement of pregnancy to determine cases where an abortion is likely to occur soon. Clinical decision-making based on ultrasound findings can improve patient management plans, patient counseling, and care for expectant patients. If prompt intervention using ultrasonographic signs improves the results of pregnancy at high risk, more research is needed to make that determination. Keywords: Ultrasonography, Threatened Abortion, Subchorionic Hematoma, and Ultrasound Markers
{"title":"Ultrasonography and Pregnancy Outcome in Threatened Abortion: A Prospective Observational Study","authors":"Sadhna Kumari, Ashutosh Kumar, Anjana Sinha, Gunjan Gunjan","doi":"10.32553/ijmbs.v8i3.2797","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i3.2797","url":null,"abstract":"Background: Women who experience vaginal bleeding in the early stages of their pregnancy should be extremely worried about the phenomenon of \"threatened abortion\". Predicting the course of a pregnancy and choosing the best management techniques are critical to providing the best possible care for patients. The purpose of this investigation's prospective observational design was to learn more about the predictive power of ultrasound and how it may affect the medical management of upcoming abortions. \u0000Method: For the study, 200 first trimester pregnant women who showed indicators of an imminent abortion were gathered between X and Y. We looked at the fetus's heart, the size of the cervical canal, and a few other parts of the gestational sac using ultrasonography. Furthermore, records pertaining to the existence of extra data, like subchorionic hematoma, were found. Numerous exams were conducted to monitor the pregnancy's development. \u0000Results: Of the research's participants, 35% miscarried for unidentified reasons, and 65% were able to bring their pregnancies to term. The pregnancy's outcome could be accurately predicted based on the ultrasonography results. More specifically, there was a significant correlation between the development of a visible gestational sac and the presence of fetal heart activity and a higher chance of a successful pregnancy outcome. This was a strong relationship. On the other hand, women who had a subchorionic hematoma or a shorter cervical length were found to have a significantly higher risk of miscarriage. These findings show the value of ultrasonography as a technique for forecasting the course of pregnancies that are at risk of ending because of difficulties connected to the threat of abortion. \u0000Conclusion: Investigation's prospective observational design shows how ultrasound can be used to evaluate the advancement of pregnancy to determine cases where an abortion is likely to occur soon. Clinical decision-making based on ultrasound findings can improve patient management plans, patient counseling, and care for expectant patients. If prompt intervention using ultrasonographic signs improves the results of pregnancy at high risk, more research is needed to make that determination. \u0000Keywords: Ultrasonography, Threatened Abortion, Subchorionic Hematoma, and Ultrasound Markers","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"142 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141281108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-02DOI: 10.32553/ijmbs.v8i1.2779
Khriztie Limanthara, S. Sadputranto, A. Yuza
Introduction: Orthognathic surgery is surgery to correct the jaw relation and which aim to correct dentoskeletal deformities and a treatment option for severe deformity that cannot be corrected by orthodontic treatment alone. Le fort I osteotomy is a technique in orthognathic surgery that aims to correct the maxilla. In its management, it is possible for correction of the maxilla and mandible to achieve an optimal jaw relation, function and esthetics. Case report: This case report explained a patient with maxilla retrognathism accompanied by function and aesthetic problems. This patient was diagnosed with class III dysgnathy and was performed orthognathic surgery treatment with le fort I osteotomy technique under general anesthesia at Central Operating Theater at Hasan Sadikin General Hospital, Bandung, and was evaluate periodically after the surgery. Conclusion: In this case, the patient's function and aesthetic problems was corrected without causing any postoperative complications. Careful planning with a good calculation and treatment plans are important for obtaining a good result. Keywords: Le fort I osteotomy, class III disgnathy, dentoskeletal deformity
简介正颌外科手术是矫正颌骨关系的手术，目的是矫正牙齿骨骼畸形，是一种治疗单靠正畸治疗无法矫正的严重畸形的方法。Le fort I 截骨术是正颌外科手术中旨在矫正上颌骨的一种技术。在治疗过程中，可以对上颌骨和下颌骨进行矫正，以达到最佳的颌骨关系、功能和美观效果：本病例报告解释了一名上颌骨后突并伴有功能和美观问题的患者。该患者被诊断为 III 级颌骨发育不良，在万隆 Hasan Sadikin 综合医院中央手术室接受了全身麻醉下的 Le fort I 截骨技术正颌外科手术治疗，术后定期接受评估。结论在这个病例中，患者的功能和美观问题得到了矫正，术后未出现任何并发症。精心的规划、良好的计算和治疗方案对获得良好的效果非常重要：Le fort I 型截骨术 III 级失认 牙槽骨畸形
{"title":"Osteotomy Le fort I as a Treatment option for class III Dentoskeletal Problem","authors":"Khriztie Limanthara, S. Sadputranto, A. Yuza","doi":"10.32553/ijmbs.v8i1.2779","DOIUrl":"https://doi.org/10.32553/ijmbs.v8i1.2779","url":null,"abstract":"Introduction: Orthognathic surgery is surgery to correct the jaw relation and which aim to correct dentoskeletal deformities and a treatment option for severe deformity that cannot be corrected by orthodontic treatment alone. Le fort I osteotomy is a technique in orthognathic surgery that aims to correct the maxilla. In its management, it is possible for correction of the maxilla and mandible to achieve an optimal jaw relation, function and esthetics.\u0000Case report: This case report explained a patient with maxilla retrognathism accompanied by function and aesthetic problems. This patient was diagnosed with class III dysgnathy and was performed orthognathic surgery treatment with le fort I osteotomy technique under general anesthesia at Central Operating Theater at Hasan Sadikin General Hospital, Bandung, and was evaluate periodically after the surgery. Conclusion: In this case, the patient's function and aesthetic problems was corrected without causing any postoperative\u0000complications. Careful planning with a good calculation and treatment plans are important for obtaining a good result.\u0000Keywords: Le fort I osteotomy, class III disgnathy, dentoskeletal deformity","PeriodicalId":14139,"journal":{"name":"International Journal of Medical and Biomedical Studies","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141018858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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